ID   A0A2K6A3T8_MANLE        Unreviewed;       268 AA.
AC   A0A2K6A3T8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Checkpoint protein {ECO:0000256|PIRNR:PIRNR011312};
GN   Name=HUS1 {ECO:0000313|Ensembl:ENSMLEP00000034731.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000034731.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000034731.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the HUS1 family. {ECO:0000256|ARBA:ARBA00005563,
CC       ECO:0000256|PIRNR:PIRNR011312}.
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DR   AlphaFoldDB; A0A2K6A3T8; -.
DR   STRING; 9568.ENSMLEP00000034731; -.
DR   Ensembl; ENSMLET00000058320.1; ENSMLEP00000034731.1; ENSMLEG00000041513.1.
DR   GeneTree; ENSGT00390000000706; -.
DR   OMA; VCWMRLE; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0030896; C:checkpoint clamp complex; IEA:Ensembl.
DR   GO; GO:0005730; C:nucleolus; IEA:InterPro.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0000077; P:DNA damage checkpoint signaling; IEA:Ensembl.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
DR   Gene3D; 3.70.10.10; -; 1.
DR   InterPro; IPR016580; Cell_cycle_HUS1.
DR   InterPro; IPR046938; DNA_clamp_sf.
DR   InterPro; IPR007150; Hus1/Mec3.
DR   PANTHER; PTHR12900:SF4; CHECKPOINT PROTEIN HUS1; 1.
DR   PANTHER; PTHR12900; MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1; 1.
DR   Pfam; PF04005; Hus1; 1.
DR   PIRSF; PIRSF011312; Cell_cycle_HUS1; 1.
DR   SUPFAM; SSF55979; DNA clamp; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140}.
SQ   SEQUENCE   268 AA;  30403 MW;  B202441E599E1E35 CRC64;
     MRFRAKIVDG ACLNHFTRIS NMIAKLAKTC TLRISPDKLN FILCDKLANG GVSMWCELEQ
     ENFFNEYQME GVSAENNEIY LELTSENLSR ALKTAQNARA LKIKLTNKHF PCLTVSVELL
     SMSSSSRIVT HDIPIKVIPR KLWKDLQEPV VPDPDFFSFC LPFLRLCKIL NLQVIEANLD
     GELNLKIETE LVCVTTHFKD LGNPPLGKCS SGLYFAFVHI DIRKLLQFLA GQQVNPTKAL
     CNIVNNKMVH FDLLHEDVSL QYFIPALS
//