ID   A0A2K6ABE4_MANLE        Unreviewed;       870 AA.
AC   A0A2K6ABE4;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=DNA polymerase kappa {ECO:0000256|ARBA:ARBA00016178};
GN   Name=POLK {ECO:0000313|Ensembl:ENSMLEP00000037370.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000037370.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000037370.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_011851892.1; XM_011996502.1.
DR   AlphaFoldDB; A0A2K6ABE4; -.
DR   STRING; 9568.ENSMLEP00000037370; -.
DR   Ensembl; ENSMLET00000060978.1; ENSMLEP00000037370.1; ENSMLEG00000042768.1.
DR   GeneID; 105551317; -.
DR   KEGG; mleu:105551317; -.
DR   CTD; 51426; -.
DR   GeneTree; ENSGT00940000156667; -.
DR   OrthoDB; 146204at2759; -.
DR   Proteomes; UP000233140; Unplaced.
DR   GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR   GO; GO:0090734; C:site of DNA damage; IEA:Ensembl.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0034644; P:cellular response to UV; IEA:Ensembl.
DR   GO; GO:0042276; P:error-prone translesion synthesis; IEA:Ensembl.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; IEA:Ensembl.
DR   CDD; cd03586; PolY_Pol_IV_kappa; 1.
DR   Gene3D; 1.10.150.810; -; 2.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.1170.60; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 2.
DR   Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR   HAMAP; MF_01113; DNApol_IV; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR   InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR   InterPro; IPR022880; DNApol_IV.
DR   InterPro; IPR024728; PolY_HhH_motif.
DR   InterPro; IPR006642; Rad18_UBZ4.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001126; UmuC.
DR   PANTHER; PTHR11076:SF33; DNA POLYMERASE KAPPA; 1.
DR   PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR   Pfam; PF00817; IMS; 1.
DR   Pfam; PF11799; IMS_C; 1.
DR   Pfam; PF11798; IMS_HHH; 1.
DR   PIRSF; PIRSF036603; DPol_eta; 2.
DR   SMART; SM00734; ZnF_Rad18; 2.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR   PROSITE; PS50173; UMUC; 1.
DR   PROSITE; PS51908; ZF_UBZ4; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|PROSITE-
KW   ProRule:PRU01256};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|PROSITE-
KW   ProRule:PRU01256}; DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU01256}.
FT   DOMAIN          103..358
FT                   /note="UmuC"
FT                   /evidence="ECO:0000259|PROSITE:PS50173"
FT   DOMAIN          777..807
FT                   /note="UBZ4-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51908"
FT   REGION          814..858
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          57..99
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        814..839
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   870 AA;  98354 MW;  3193AE5A41895A73 CRC64;
     MDSIKEKCDS YKDDLLLRMG LNDNKAGMEG LDKEKINKII MEATKGSRFY GNELKKEKQV
     NQRIENMMQQ KAQITSQQLR KAQLQVDRFA MELEQSRNLS NTIVHIDMDA FYAAVEMRDN
     PELKDKPIAV GSMSMLSTSN YHARRFGVRA AMPGFIAKRL CPQLIIVPPN FDKYRAVSKE
     VKEILADYDP NFMAMSLDEA YLNITKHLEE RQNWPEDKRK YFIKMGNSVE NDNPGKEVNK
     LSDHERSISP LLFEESPSDL LPPGDPFQVN FEEQNSPQIL QNSIVFGTSA EEVVKEIRFR
     IEQKTTLTAS AGIAPNTMLA KVCSDKNKPN GQYQILPNRQ AVMDFIKDLP IRKVSGIGKV
     TEKMLKALGI ITCTELYQQR ALLSLLFSET SWHYFLHISL GLGSTYLTRD GERKSMSVER
     TFSEINKAEE QYSLCEELCS ELARDLQKEG LKGRTVTIKL KNVNFEVKTR ASTVSSVVST
     AEEIFAIAKE LLKTEIDADF PHPLRLRLMG VRISSFPNEE DRKHQQRSII GFLQTGNQAL
     SATGCILEKT DKDQFVKPLE MSHKKSFFDK KRSERKWSHQ DTFKCETVNK QSFQTSQPFQ
     VLKKKMSENL EISENSDNCQ IFTCPVCFRA QGCISLEAFN KHVDACLDGS SISENSKVFS
     CSHVSATRVN KKENVPASSL CEKQDYEAHP KIKEVSSVDC VALVDTIDNS SKAESIDALS
     NKHIKGECSN LPGKSFNIEH CHQNSSCTVS LENEDVGLLS RQESCEPYLC EVITGQALIC
     PVCNVEQKTS DLTLFNVHVD VCLNKSFIQE LRNDKVNPVN QPKESSRSTG SSSGVQKAVT
     KTKRPGLMTK YSSKKIKPNN PKHTLDIFFK
//