ID A0A2K6ADY8_MANLE Unreviewed; 410 AA.
AC A0A2K6ADY8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=ethanolamine kinase {ECO:0000256|ARBA:ARBA00038874};
DE EC=2.7.1.82 {ECO:0000256|ARBA:ARBA00038874};
GN Name=CHKA {ECO:0000313|Ensembl:ENSMLEP00000038228.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000038228.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000038228.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.
CC {ECO:0000256|ARBA:ARBA00037883}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2K6ADY8; -.
DR STRING; 9568.ENSMLEP00000038228; -.
DR Ensembl; ENSMLET00000061838.1; ENSMLEP00000038228.1; ENSMLEG00000043175.1.
DR GeneTree; ENSGT00950000182939; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0004103; F:choline kinase activity; IEA:Ensembl.
DR GO; GO:0004104; F:cholinesterase activity; IEA:Ensembl.
DR GO; GO:0004305; F:ethanolamine kinase activity; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:Ensembl.
DR CDD; cd05156; ChoK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603:SF36; CHOLINE KINASE ALPHA; 1.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233140}.
SQ SEQUENCE 410 AA; 47665 MW; B6DE1CCD454D4417 CRC64;
FFFETESRSV SQAGVQWRDL RSSQAPSPPG FTPFSCLSVP SSWDYRRPPS RPANFFVFLV
ETGFHSVRQD GGLSNMLFQC SLPDTTATLG DEPRKVLLRL YGAILQMRSC NKEGSEQAQK
ENEFQGAEAM VLESVMFAIL AERSLGPKLY GIFPQGRLEQ FIPSRRLDTE ELSLPDISAE
IAEKMATFHG MKMPFNKEPK WLFGTMEKYL NEVLRIKFTE ESRIKKLHKL LSYNLPLELE
NLRSLLESTP SPVVFCHNDC QEGNILLLEG QENSEKQKLM LIDFEYSSYN YRGFDIGNHF
CEWMYDYSYE KYPFFRANIR KYPTKKQQLH FISSYLPAFQ NDFENLSTEE KSIIEEEMLL
EVNRFALASH FLWGLWSIVQ AKISSIEFGY MDYAQARFDA YFHQKRKLGV
//
