ID   A0A2K6AET1_MANLE        Unreviewed;      1164 AA.
AC   A0A2K6AET1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Formin homology 2 domain containing 1 {ECO:0000313|Ensembl:ENSMLEP00000038550.1};
GN   Name=FHOD1 {ECO:0000313|Ensembl:ENSMLEP00000038550.1};
OS   Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Mandrillus.
OX   NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000038550.1, ECO:0000313|Proteomes:UP000233140};
RN   [1] {ECO:0000313|Ensembl:ENSMLEP00000038550.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_011852073.1; XM_011996683.1.
DR   AlphaFoldDB; A0A2K6AET1; -.
DR   Ensembl; ENSMLET00000062162.1; ENSMLEP00000038550.1; ENSMLEG00000043304.1.
DR   GeneID; 105551452; -.
DR   CTD; 29109; -.
DR   GeneTree; ENSGT00940000160212; -.
DR   OrthoDB; 2918313at2759; -.
DR   Proteomes; UP000233140; Unplaced.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR041387; FHOD1_GBD_N.
DR   InterPro; IPR014768; GBD/FH3_dom.
DR   PANTHER; PTHR45920:SF2; FH1_FH2 DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR45920; FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I; 1.
DR   Pfam; PF02181; FH2; 1.
DR   Pfam; PF18382; Formin_GBD_N; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
DR   PROSITE; PS51232; GBD_FH3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233140}.
FT   DOMAIN          53..458
FT                   /note="GBD/FH3"
FT                   /evidence="ECO:0000259|PROSITE:PS51232"
FT   DOMAIN          616..1013
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          339..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          469..500
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          567..619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          997..1104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1117..1143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..369
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..414
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        570..610
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        997..1016
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1164 AA;  126904 MW;  BAA26DF972AA69A8 CRC64;
     MAGGEDRGDE EPVSVVTVRV QYLEDTDPFA CANFPEPRRA PTCSLDGALP LGAQIPALHR
     LLGAPLKLED CALQVSPSGY YLDPELSLEE QREMLEGFYE EISKGRKPTL ILRTQLSVRV
     NAILEKLYGS SGPELRRSLF SLKQIFQEDK DLVPEFVHSE GLSCLIRVGA AADHNYQSYI
     LRALGQLMLF VDGMLGVVAH SETIQWLYTL CASLSRLVVK TALKLLLVFV EYSENNAPLF
     ICAVNSVASA TGAPPWANLV SILEEKNGTD PELLVYTVTL INKTLAALPD QDSFYDVTDA
     LEQQGMEALV QRHLGTAGTD VDLRTQLVLY ENALKLEDGD IEEAPGGGGR RERRKPSSEE
     GKRSRRSLEG GGCPARALEP GPTGPASPVG LTSSTSPAPL TGPTSSPVGP PSGLRASVNL
     FPTISVAPSA DTSSERSIYK ARFLENVAAA ETEKQVALAQ GRAETLAEAM PSEADGHPDA
     RQLWDSPETA PAPRTPQSPA PCVLLRAQRS LEPEPKEPLM PASPKAEPIW ELPTRAPNLS
     IGDLDFSDLG EEEDQDMLNV ESVEAGKEVP APAPPLPLLS GVPPPPPPPP PPPIKGPFPP
     PPPLPLAAPL PHSLPDSSAL PTKRKTVKLF WRELKLAGGH GVSASRFGPC ATLWASLEPV
     SVDTARLEHL FESRAKEVLP SKKAGEGRRT MTTVLDPKRS NAINIGLTTL PPVHVIKAAL
     LNFDEFAVSK DGIEKLLTMM PTEEEQQKIE EAQLANPDIP LGPAENFLMT LASIGGLAAR
     LQLWAFKLDY DSMEREIAEP LFDLKVGMEQ LVQNATFRCI LATLLAVGNF LNGSQSSGFE
     LSYLEKVSEV KDTVRRQSLL HHLCSLVLQT RPESSDLYSE IPALTRCAKV DFEQLTENLG
     QLERRSWAAE ESLRSLAKHE LALALRARLT HFLAQRARRV AMLRIVHRRV CNRFHAFLLY
     LGYTPQAARE VRITQFCHTL REFALEYRTC RERVLQQQQK RATYRERNKT RGRMITETEK
     FSGVAGEAPN NPSVPVAVSS GPGRGDADSH ASMKSLLTSR PEDTTHNRRS RGMVQSSSPV
     MPTVGPSTVP PEEPPGSSLP SDTSDEIMDL LVQSVTKSSP RALAARERKR SRGNRKSLRR
     TLKSGLGDDL VQALGLSKGP GLEV
//