ID A0A2K6AHA1_MANLE Unreviewed; 359 AA.
AC A0A2K6AHA1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Zinc transporter ZIP13 {ECO:0000256|ARBA:ARBA00040592};
DE AltName: Full=Solute carrier family 39 member 13 {ECO:0000256|ARBA:ARBA00042542};
DE AltName: Full=Zrt- and Irt-like protein 13 {ECO:0000256|ARBA:ARBA00042972};
GN Name=SLC39A13 {ECO:0000313|Ensembl:ENSMLEP00000039444.1};
OS Mandrillus leucophaeus (Drill) (Papio leucophaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Mandrillus.
OX NCBI_TaxID=9568 {ECO:0000313|Ensembl:ENSMLEP00000039444.1, ECO:0000313|Proteomes:UP000233140};
RN [1] {ECO:0000313|Ensembl:ENSMLEP00000039444.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Zn(2+)(in) = Zn(2+)(out); Xref=Rhea:RHEA:29351,
CC ChEBI:CHEBI:29105; Evidence={ECO:0000256|ARBA:ARBA00034634};
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004156}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000256|ARBA:ARBA00006939}.
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DR AlphaFoldDB; A0A2K6AHA1; -.
DR Ensembl; ENSMLET00000063062.1; ENSMLEP00000039444.1; ENSMLEG00000043749.1.
DR GeneTree; ENSGT00940000157349; -.
DR Proteomes; UP000233140; Unplaced.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR16950; ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4; 1.
DR PANTHER; PTHR16950:SF16; ZINC TRANSPORTER ZIP13; 1.
DR Pfam; PF02535; Zip; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233140};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..359
FT /note="Zinc transporter ZIP13"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014427055"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 359 AA; 37779 MW; 1011E3DC5698FBF8 CRC64;
MPGCPCPGCG MAGPRLLFLT ALALELLGRA GGSHPALRSR GTATACRLDN KESESWGALL
SGERLDTWIC SLLGSLMVGL SGVFPLLVIP LEMGTMLRSE AGAWRLKQLL SFALGGLLGN
VFLHLLPEAW AYTCSAGPGG EGQSLQQQQQ LGLWVIAGIL TFLALEKMFL DSKAERTSQA
PNKDPTAAAA ALNGGHCLAQ PAAEPGLGAV VRSIKVSGYL NLLANTIDNF THGLAVAASF
LVSKKVRGLG LVGDFAILLR AGFDRWSAAK LQLSTALGGL LGAGFAICTQ SPKGVEETAA
WVLPFTSGGF LYIALVNVLP DLLEEEDPWA LKRLRREGLL LLLLCAGIVV MVLFSIFVD
//
