ID A0A2K6AS52_MACNE Unreviewed; 386 AA.
AC A0A2K6AS52;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Histone-binding protein RBBP4 N-terminal domain-containing protein {ECO:0000259|Pfam:PF12265};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000001980.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000001980.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome, telomere
CC {ECO:0000256|ARBA:ARBA00004574}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
CC {ECO:0000256|ARBA:ARBA00009341}.
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DR AlphaFoldDB; A0A2K6AS52; -.
DR Ensembl; ENSMNET00000009785.1; ENSMNEP00000001980.1; ENSMNEG00000008849.1.
DR GeneTree; ENSGT00940000153375; -.
DR OMA; CEDWIIS; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000008849; Expressed in lymph node and 8 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR022052; Histone-bd_RBBP4_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22850:SF90; HISTONE-BINDING PROTEIN RBBP4; 1.
DR PANTHER; PTHR22850; WD40 REPEAT FAMILY; 1.
DR Pfam; PF12265; CAF1C_H4-bd; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Telomere {ECO:0000256|ARBA:ARBA00022895};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 19..88
FT /note="Histone-binding protein RBBP4 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12265"
FT REPEAT 162..197
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 212..254
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 267..289
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 291..333
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 348..386
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 386 AA; 43428 MW; 4760FA84F6E6ACD2 CRC64;
MADKEAAFDD AVEERVIHKE YKIWKKNTPF LYDLVMTQAL EWPSLTAQWL PGVTRPEGKD
FSIHQLVLGT LTSDVQNHLV IVSVQLPNDD AQCDASYYDI SGKIEIEIKI NHEGEVNRAH
YVPQNPCIIT TKTPSSDVLV FDYTKHPSKP DLSGECNPDL RLRGHQKEGY GLSWNPNLSG
HLLGASDDHT ICLWDISAVP KEGKVVDVKT IFTGHTAVVE DVSWHLLHES LFVSVADDQK
LMIWDTRSNN TSKPRHSADA HTAEFILATG SADKTVALWD LKNLKLMSHF FESRKDEIFQ
VQWSPHNEAI LASSGTDHRM NVWDLSKIGE EQSPDDAEDG PPALLFIHGG HTAKISDFSW
NPNESWVICS VSEDNILQVW QMSENI
//
