ID A0A2K6ASU8_MACNE Unreviewed; 347 AA.
AC A0A2K6ASU8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Growth arrest specific 1 {ECO:0000313|Ensembl:ENSMNEP00000002220.1};
GN Name=GAS1 {ECO:0000313|Ensembl:ENSMNEP00000002220.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000002220.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000002220.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011769408.1; XM_011771106.1.
DR AlphaFoldDB; A0A2K6ASU8; -.
DR STRING; 9545.ENSMNEP00000002220; -.
DR Ensembl; ENSMNET00000011123.1; ENSMNEP00000002220.1; ENSMNEG00000010226.1.
DR GeneID; 105498772; -.
DR KEGG; mni:105498772; -.
DR CTD; 2619; -.
DR GeneTree; ENSGT00390000001195; -.
DR OMA; NRYLTYC; -.
DR OrthoDB; 5323788at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000010226; Expressed in bone marrow and 8 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IEA:Ensembl.
DR GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0010955; P:negative regulation of protein processing; IEA:Ensembl.
DR GO; GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IEA:Ensembl.
DR InterPro; IPR039596; GAS1.
DR InterPro; IPR016017; GDNF/GAS1.
DR PANTHER; PTHR16840; GROWTH ARREST-SPECIFIC PROTEIN 1; 1.
DR PANTHER; PTHR16840:SF3; GROWTH ARREST-SPECIFIC PROTEIN 1; 1.
DR Pfam; PF02351; GDNF; 1.
DR SMART; SM00907; GDNF; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..39
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 40..347
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014409362"
FT DOMAIN 48..148
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT DOMAIN 168..245
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT REGION 256..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 35805 MW; 179B8426C4D6782C CRC64;
MVAALLGGGG EARGGTVPGA WLCLMALLQL LGSAPRGSGL AHGRRLICWQ ALLQCQGEPE
CSYAYNQYAE ACAPVLAQHG GGDAPGAAAA AAAFPASAAS FSSRWRCPSH CISALIQLNH
TRRGPALEDC DCAQDENCKS TKRAIEPCLP RTSGGGAGGP GAGGVMGCTE ARRRCDRDSR
CNLALSRYLT YCGKVFNGLR CTDECRTVIE DMLAMPKAAL LNDCVCDGLE RPICESVKEN
MARLCFGAEL GNGPGSSGSD GGLDDYYDED YDDEQRPGGA GGEQPLDDDD GVPHPPRPGS
GAAAAGGRGD LPYGPGRRSS GGGGRSAPRG AWTPLASILL LLLGLLF
//
