ID A0A2K6AT27_MACNE Unreviewed; 443 AA.
AC A0A2K6AT27;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Solute carrier family 10 member 5 {ECO:0000313|Ensembl:ENSMNEP00000002299.1};
GN Name=SLC10A5 {ECO:0000313|Ensembl:ENSMNEP00000002299.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000002299.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000002299.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the bile acid:sodium symporter (BASS) (TC
CC 2.A.28) family. {ECO:0000256|ARBA:ARBA00006528}.
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DR RefSeq; XP_011742699.1; XM_011744397.1.
DR AlphaFoldDB; A0A2K6AT27; -.
DR STRING; 9545.ENSMNEP00000002299; -.
DR Ensembl; ENSMNET00000011539.1; ENSMNEP00000002299.1; ENSMNEG00000010613.1.
DR GeneID; 105483510; -.
DR KEGG; mni:105483510; -.
DR GeneTree; ENSGT00950000182808; -.
DR OMA; KHRIPEK; -.
DR OrthoDB; 4326770at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000010613; Expressed in liver and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR InterPro; IPR004710; Bilac:Na_transpt.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR10361; SODIUM-BILE ACID COTRANSPORTER; 1.
DR PANTHER; PTHR10361:SF29; SODIUM_BILE ACID COTRANSPORTER 5; 1.
DR Pfam; PF01758; SBF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Signal {ECO:0000256|SAM:SignalP}; Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022847}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..443
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014439810"
FT TRANSMEM 181..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 443 AA; 49367 MW; EF9B0333788088E4 CRC64;
MSAFKMIRKL FIVLLLLLVT IEEARMSSLG FLNIEKTEIL FFTKTEETII VSSRYEDKQP
NSSHLFVKIE DPKILQMVNV TKKISSDATD FTINLVTDEE GETNMTIQLW DSEGRQERLI
EEIKNVKVKV LKQKDSLLQA SMPIDRNILM LILPLILLNK CAFGCKIELQ VFQTVWKRPL
PVILGAVTQF FLMPFCGFLL SQIVALREAQ AFGVVMTCTC PGGGGGYLFA LLLDGDFTLA
ILMTCTSTFL ALIVMPVNSY IYSKILGLSG TFHIPVSKIV STLLFILVPV SIGIVIKHRI
PEKASFLERI IRPLSFILMF VGIYLTFAVG LMFLKTDNLE VILLGLLVPA LGLLFGYSFA
KVCMLPLPVC KTVAIESGML NSFLALAIIQ LSFPQSKANL ASVAPFTVAM CSGCEMLLII
LVYKAKKGCI FFLQDKRKRN SLI
//
