ID A0A2K6AUB7_MACNE Unreviewed; 609 AA.
AC A0A2K6AUB7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Zinc finger protein 527 {ECO:0000313|Ensembl:ENSMNEP00000002734.1};
GN Name=ZNF527 {ECO:0000313|Ensembl:ENSMNEP00000002734.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000002734.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000002734.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR RefSeq; XP_011763280.1; XM_011764978.1.
DR AlphaFoldDB; A0A2K6AUB7; -.
DR Ensembl; ENSMNET00000013819.1; ENSMNEP00000002734.1; ENSMNEG00000012680.1.
DR GeneID; 105495435; -.
DR KEGG; mni:105495435; -.
DR CTD; 84503; -.
DR GeneTree; ENSGT00940000162987; -.
DR OMA; KEPWMVQ; -.
DR OrthoDB; 3120634at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000012680; Expressed in cerebellum and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 12.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF90; KRAB DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 11.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 11.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 11.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 12.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 14..85
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 274..301
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 302..329
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 330..357
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 358..385
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 386..413
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 414..441
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 442..469
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 470..497
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 498..525
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 526..553
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 554..581
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 582..609
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 609 AA; 70935 MW; B7E737787C23ACF7 CRC64;
MAVGLCKAMS QGLVTFRDVA LDFSQEEWEW LKPSQKDLYR DVMLENYRNL VWLGLSISKP
NMISLLEQGK EPWMVERKMS QGHCADWESW CEIKELSPKW FIDEDEISQE MIMERLTSHG
LECSSFREAW KCKGEFELHE GNAERHFMQV TAVKKISTGK RHNEFSNFGR SIPRKSVFLT
QQKVPTIEQV HKFDIYDKLF PQNSVIIEYK RLRAEKESLI GNECEEFNQS TYFSKDTGIP
LGEKPYESND FSNLLSFHSL LAQHQKTHFG KLPHGYSECG DAFSCYSFFT QPQRIHSGEK
PYACNDCGKA FSHGFFLSEH QRTHIGEKPY ECKECNKAFR QSAHLAQHQR IHTGEKPFAC
NECGKAFSRY AFLVEHQRIH TGEKPYECKE CNKAFRQSAH LNQHQRIHTG EKPYECNQCG
KAFSRRIALT LHQRIHTGEK PFKCSECGKT FGYRSHLNQH QRIHTGEKPY ECIKCGKFFR
TDSQLNRHHR IHTGERPFEC SKCGKAFSDA LVLIHHKRSH AGEKPYECNK CGKAFSCGSY
LNQHQRIHTG EKPYECNECG KAFHQILSLR LHQRIHAGEK PYKCNECGNN FSCVSALRRH
QRIHNRETL
//
