ID A0A2K6AV60_MACNE Unreviewed; 486 AA.
AC A0A2K6AV60;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Tripartite motif containing 58 {ECO:0000313|Ensembl:ENSMNEP00000003030.1};
GN Name=TRIM58 {ECO:0000313|Ensembl:ENSMNEP00000003030.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000003030.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000003030.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_011727876.1; XM_011729574.1.
DR AlphaFoldDB; A0A2K6AV60; -.
DR STRING; 9545.ENSMNEP00000003030; -.
DR Ensembl; ENSMNET00000015332.1; ENSMNEP00000003030.1; ENSMNEG00000014084.1.
DR GeneID; 105474740; -.
DR KEGG; mni:105474740; -.
DR CTD; 25893; -.
DR GeneTree; ENSGT00940000162246; -.
DR OMA; HLERPRC; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000014084; Expressed in bone marrow and 1 other cell type or tissue.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19780; Bbox2_TRIM39-like; 1.
DR CDD; cd16606; RING-HC_TRIM58_C-IV; 1.
DR CDD; cd15816; SPRY_PRY_TRIM58; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR035787; SPRY/PRY_TRIM58.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR042699; TRIM58_RING-HC.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF393; E3 UBIQUITIN-PROTEIN LIGASE TRIM58; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 16..61
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 91..132
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 273..463
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 194..239
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 486 AA; 54939 MW; AFDE2D8E2B285E48 CRC64;
MASGPPGERL REEARCPVCL DFLQEPVSVD CGHSFCLRCI SEFCEKSDIA QGGVYACPQC
RGPFRPAGFR PNRQLAGLVD SVRRLGLGAG PGARRCALHG EELSRFCEED QAALCWVCDA
GPDHRTHRTA PLQEAAGRYQ VKLQMALELV RKELEDALTQ EASVGKKTVI WKEKVEMQRQ
RFRLEFEKHR GFLAQEEQLQ LRRLEAEERA TLQRLRESKS RLVQQSKALK ELADELQERC
QRQALGLLEG VKGVLSRSKA VTRLETESIP MELKTACRIP GRRELLRKFQ VDVKLDPATA
HPSLLLTADL RSVQDGELWR DVPNNPERFD TWPCILGLQS FSSGRHYWEV LVEERAEWGL
GVCQDTLPRK GETTPSPENG VWALWLLKGN EYMVLASSSV PLLLLESPRC IGIFLDYEAG
EITFYNVTNG SYIYTFNQLF SGLLRPYFFI CDATPLILPP MTVAESGNWA SRDHLDPASD
VRDDHL
//
