ID A0A2K6AW61_MACNE Unreviewed; 158 AA.
AC A0A2K6AW61;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Transmembrane protein 50B {ECO:0000256|ARBA:ARBA00041170};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000003382.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000003382.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: May form homotrimers or homodimers.
CC {ECO:0000256|ARBA:ARBA00038714}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the UPF0220 family.
CC {ECO:0000256|ARBA:ARBA00005335}.
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DR RefSeq; XP_011724511.1; XM_011726209.1.
DR RefSeq; XP_011724513.1; XM_011726211.1.
DR RefSeq; XP_011724514.1; XM_011726212.1.
DR AlphaFoldDB; A0A2K6AW61; -.
DR Ensembl; ENSMNET00000017129.1; ENSMNEP00000003382.1; ENSMNEG00000015660.1.
DR GeneID; 105472703; -.
DR KEGG; mni:105472703; -.
DR CTD; 757; -.
DR GeneTree; ENSGT00940000155131; -.
DR OMA; LWIMFAD; -.
DR OrthoDB; 5392709at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000015660; Expressed in heart and 12 other cell types or tissues.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007919; UPF0220.
DR PANTHER; PTHR13180; SMALL MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR13180:SF2; TRANSMEMBRANE PROTEIN 50B; 1.
DR Pfam; PF05255; UPF0220; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 158 AA; 17936 MW; 515ABB6AAA817DEB CRC64;
MAGFLDNFRW PECECIDWSE RRNAVASVVA GILFFTGWWI MIDAAVVYPK PEQLNHAFHT
CGVFSTLAFF MINAVSNAQV RGDSYESGCL GRTGARVWLF IGFMLMFGSL IASMWILFGA
YVTQNTDVYP GLAVFFQNAL IFFSTLIYKF GRTEELWT
//
