ID   A0A2K6AWM9_MACNE        Unreviewed;       907 AA.
AC   A0A2K6AWM9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=RAD54 homolog B {ECO:0000313|Ensembl:ENSMNEP00000003548.1};
GN   Name=RAD54B {ECO:0000313|Ensembl:ENSMNEP00000003548.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000003548.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000003548.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family.
CC       {ECO:0000256|ARBA:ARBA00007025}.
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DR   RefSeq; XP_011766515.1; XM_011768213.1.
DR   AlphaFoldDB; A0A2K6AWM9; -.
DR   STRING; 9545.ENSMNEP00000003548; -.
DR   Ensembl; ENSMNET00000017990.1; ENSMNEP00000003548.1; ENSMNEG00000016408.1.
DR   GeneID; 105497240; -.
DR   KEGG; mni:105497240; -.
DR   CTD; 25788; -.
DR   GeneTree; ENSGT00940000156966; -.
DR   OrthoDB; 5480555at2759; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000016408; Expressed in pituitary gland and 12 other cell types or tissues.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR   GO; GO:0015616; F:DNA translocase activity; IEA:Ensembl.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0009410; P:response to xenobiotic stimulus; IEA:Ensembl.
DR   CDD; cd18066; DEXHc_RAD54B; 1.
DR   CDD; cd18793; SF2_C_SNF; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.20.120.850; SWI2/SNF2 ATPases, N-terminal domain; 1.
DR   Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR049730; SNF2/RAD54-like_C.
DR   InterPro; IPR000330; SNF2_N.
DR   PANTHER; PTHR45629:SF7; DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED; 1.
DR   PANTHER; PTHR45629; SNF2/RAD54 FAMILY MEMBER; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00176; SNF2-rel_dom; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT   DOMAIN          312..479
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          647..808
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   907 AA;  102598 MW;  9AEE1E4C2EB72C88 CRC64;
     MRRSAAPSQL QGNSFKKPKF IPPGRSNPGL NEEITKLNPD IKLFEGAANN TFLPSQRDPR
     ICSLNLPNEE STREINYTDN CSGKYCFEAP TLATLDPPHT VHLTPKEVAV SKEQEETSDS
     LVKYFSVVWC KPSKKKHKKW EGDAVLIVKG KSFILKNLEG KDIGRGIGYK FKELEKIEEG
     QTLMICGKEI EVMGVVSPDD FSSGRCFQLG GGSTAISRSS QAARKCFSNP FKSVCKPSSK
     ENRQNDFQNC KPRHDPYTPN SLVMPRPDKN HQWVFNKNCF PLVDVVIDPY LVYHLRPHQK
     EGIIFLYECV MGMRMNGRCG AILADEMGLG KTLQCISLIW TLQCQGPYGG KPVIKKTLIV
     TPGSLVNNWK KEFQKWLGSE RIKIFTVDQD HKVEEFIKSI FYSVLIISYE MLLRSLDQIK
     NIKFDLLICD EGHRLKNSAI KTTAALISLS CEKRIILTGT PVQNDLQEFF ALIDFVNPGI
     LGSLSSYRKI YEEPIILSRE PSASEEEKEL GERRATELAC LTGLFILRRT QEIINKYLPP
     KIENVIFCRP GALQIELYRK LLNSQVVRFC LQGLLENSPH LICIGALKKL CNHPCLLFNS
     IKEKECSTCD KNEEKSLYKG LLSVFPADYN PLLFTEKESG KLQVLSKLLA VIHELRPTEK
     VVLVSNYTQT LNILQEVCKR HGYAYTRLDG QTPISQRQQI VDGFNSQHSS VFIFLLSSKA
     GGVGLNLIGG SHLILYDIDW NPATDIQAMS RVWRDGQKYP VHIYRLLTTG TIEEKIYQRQ
     ISKQGLCGAV VDLTKTSEHI QFSVEELKNL FTLHESSDCV THDLLDCECT GEVHTGDSLE
     KFIVSRDCQL GPHHQKSNSL KPLSMSQLKQ WKHFSGDHLK ITDPFLERIT ENVSFIFQNI
     TTQATGT
//