ID A0A2K6B8A0_MACNE Unreviewed; 372 AA.
AC A0A2K6B8A0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Four and a half LIM domains 2 {ECO:0000313|Ensembl:ENSMNEP00000007590.1};
GN Name=FHL2 {ECO:0000313|Ensembl:ENSMNEP00000007590.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000007590.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000007590.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011753828.1; XM_011755526.1.
DR AlphaFoldDB; A0A2K6B8A0; -.
DR Ensembl; ENSMNET00000031754.1; ENSMNEP00000007590.1; ENSMNEG00000028349.1.
DR GeneID; 105490162; -.
DR KEGG; mni:105490162; -.
DR CTD; 2274; -.
DR GeneTree; ENSGT00950000183028; -.
DR OMA; CAKCYED; -.
DR OrthoDB; 370973at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000028349; Expressed in heart and 12 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd09422; LIM1_FHL2; 1.
DR CDD; cd09426; LIM2_FHL2; 1.
DR CDD; cd09431; LIM3_Fhl2; 1.
DR CDD; cd09433; LIM4_FHL2; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24205; FOUR AND A HALF LIM DOMAINS PROTEIN; 1.
DR PANTHER; PTHR24205:SF3; FOUR AND A HALF LIM DOMAINS PROTEIN 2; 1.
DR Pfam; PF00412; LIM; 4.
DR SMART; SM00132; LIM; 4.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 5.
DR PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE 4: Predicted;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 131..191
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 192..253
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 312..372
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..83
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 372 AA; 42177 MW; 5026B78689664699 CRC64;
MTRRGFSRAG AAQRSTRPAA EQQPPAARAR PRRPGVPGPL RRREYLQLPA PRREAEGLSH
QDSEEGAESG ARPGERGADP ELGRPVAEKA GVKMTERFDC HHCNESLFGK KYILREESPY
CVACFETLFA NTCEECGKPI GCDCKDLSYK DRHWHEACFH CSQCRNSLVD KPFAAKEDQL
LCTDCYSNEY SSKCQECKKT IMPGTRKMEY KGSSWHETCF ICHRCQQPIG TKSFIPKDNQ
NFCVPCYEKQ HAMQCVQCKK PITTGGVTYR EQPWHKECFV CTACRKQLSG QRFTARDDFA
YCLNCFCDLY AKKCAGCTNP ISGLGGTKYI SFEERQWHND CFNCKKCSLS LVGRGFLTER
DDILCPDCGK DI
//
