ID   A0A2K6BEX3_MACNE        Unreviewed;       821 AA.
AC   A0A2K6BEX3;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=M-phase phosphoprotein 8 {ECO:0000313|Ensembl:ENSMNEP00000009954.1};
GN   Name=MPHOSPH8 {ECO:0000313|Ensembl:ENSMNEP00000009954.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000009954.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000009954.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A2K6BEX3; -.
DR   Ensembl; ENSMNET00000034130.1; ENSMNEP00000009954.1; ENSMNEG00000029396.1.
DR   GeneTree; ENSGT00730000111087; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000029396; Expressed in pituitary gland and 12 other cell types or tissues.
DR   CDD; cd18633; CD_MMP8; 1.
DR   Gene3D; 2.40.50.40; -; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR   InterPro; IPR023780; Chromo_domain.
DR   InterPro; IPR023779; Chromodomain_CS.
DR   PANTHER; PTHR24184:SF28; CHROMO DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR24184; SI:CH211-189E2.2; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00385; Chromo; 1.
DR   SMART; SM00248; ANK; 4.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF54160; Chromo domain-like; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 2.
DR   PROSITE; PS50088; ANK_REPEAT; 3.
DR   PROSITE; PS00598; CHROMO_1; 1.
DR   PROSITE; PS50013; CHROMO_2; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1..43
FT                   /note="Chromo"
FT                   /evidence="ECO:0000259|PROSITE:PS50013"
FT   REPEAT          534..566
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          567..599
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          600..632
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REGION          63..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          140..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          392..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..121
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        140..195
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        210..263
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..308
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        333..375
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   821 AA;  93009 MW;  72FDE15C291C9F34 CRC64;
     MKTEGGKVLY KVRWKGYTSD DDTWEPEIHL EDCKEVLLEF RKKIAENKAK AVRKDIQRLS
     LNNDIFEANS DSDQQSETKE DTSPKKKKKK LRQREEKSPD DLKKKKAKAG KLKDKSKSDL
     ESSLESLVFD LRTKKRISEA KEELKESKKP KKDEVKETKE LKKVKKGEIR DLKTKTREDP
     KENRKTKKEK CVESQVESES SVLNDSAFPE DDSEGLHSDS REEKQNTKTA RERAGQDTGL
     EHGFEKPLDS AMSAEEDTDV RGRRKKKTPR KAEDTRESRK PENKNAFLEK KTVPKKQRNQ
     DRGRSAAESE KLMPVSAQTP KGWRLSGEER GFWSTDSAEE DKETKKTESK EKYQKRHDSD
     KEEKGRKEPK GLKTLKEIRN AFDLFKLTPE EKNDVSENNR KREEIPLDFK TIDDHKTKEN
     KQSLKERRNT RDETDTWAYI AAEGDQEGSD SVCQADENSD GRQQILSLGM DLQLEWMKLE
     DFQKHLDGKD ENFAAADAIP SNVLRDAVKN GDYITVKVAL NSNEEYNLDQ EDSSGMTLVM
     LAAAGGQDDL LRLLITKGAK VNGRQKNGTT ALIHAAEKNF LTTVAILLEA GAFVNVQQSN
     GETALMKACK RGNSDIVRLV IECGADCNIL SKHQNSALHF AKQSNNVLVY DLLKSHLETL
     SRVAEETIKD YFEARLALLE PVFPIACHRL CEGPDFSTDF NYKPPQNIPE GSGILLFIFH
     ANFLGKEVIA RLCGPCSVQA VVLNDKFQLP VFLDSHFVYS FSPIAGPNKL FIRLTEAPSA
     KVTILSSYVV SVLKLLLQIT LSALEKNSKN PGVPVLERRT P
//