ID   A0A2K6BHC0_MACNE        Unreviewed;       291 AA.
AC   A0A2K6BHC0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Spectrin repeat containing nuclear envelope family member 4 {ECO:0000313|Ensembl:ENSMNEP00000010787.1};
GN   Name=SYNE4 {ECO:0000313|Ensembl:ENSMNEP00000010787.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000010787.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000010787.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the nesprin family.
CC       {ECO:0000256|ARBA:ARBA00008619}.
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DR   AlphaFoldDB; A0A2K6BHC0; -.
DR   Ensembl; ENSMNET00000034968.1; ENSMNEP00000010787.1; ENSMNEG00000029792.1.
DR   GeneTree; ENSGT00510000049061; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000029792; Expressed in cerebellum.
DR   GO; GO:0034993; C:meiotic nuclear membrane microtubule tethering complex; IEA:InterPro.
DR   InterPro; IPR012315; KASH.
DR   InterPro; IPR030268; SYNE4.
DR   PANTHER; PTHR21640:SF1; NESPRIN-4; 1.
DR   PANTHER; PTHR21640; UNCHARACTERIZED; 1.
DR   Pfam; PF10541; KASH; 1.
DR   SMART; SM01249; KASH; 1.
DR   PROSITE; PS51049; KASH; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU00385}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU00385};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TOPO_DOM        1..242
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TOPO_DOM        264..291
FT                   /note="Perinuclear space"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT   DOMAIN          234..291
FT                   /note="KASH"
FT                   /evidence="ECO:0000259|PROSITE:PS51049"
FT   REGION          1..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          200..234
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..55
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   291 AA;  31382 MW;  DC56BAF4B0ACD5F4 CRC64;
     MALSLPLGPR LGSEPFNHPP GAPREPDIVG CTVCPASGEE GTSPEQAQTL RQDSLDPPEH
     FQGGPGGNEP AAQPARWSTP SSYKDPAGGK HCEVFEEANT LDQDLEFEGD LDWRARGGVW
     GPWAPSSLPT SAELEWDPAG DIGGLGPLGQ KTAWTLGVPC ELCGHRGPQG RGQVLEEPHT
     SHSRQDMLES GLSYRKHLAG HQRRSLLRKP QDKKRQASPH LQDMRLEGNP GAPDPASRRP
     LTFLLILFLL FLLLVGAMFL LPVSGGPCCS NARIPRTPYL VLSYVNGLPP V
//