ID   A0A2K6BIS7_MACNE        Unreviewed;      1060 AA.
AC   A0A2K6BIS7;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=PAX-interacting protein 1 {ECO:0000256|ARBA:ARBA00023858};
DE   AltName: Full=PAX transactivation activation domain-interacting protein {ECO:0000256|ARBA:ARBA00030146};
GN   Name=PAXIP1 {ECO:0000313|Ensembl:ENSMNEP00000011302.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000011302.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000011302.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K6BIS7; -.
DR   Ensembl; ENSMNET00000035485.1; ENSMNEP00000011302.1; ENSMNEG00000029988.1.
DR   GeneTree; ENSGT00940000155757; -.
DR   OMA; QNYVLRD; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000029988; Expressed in cerebellum and 12 other cell types or tissues.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   CDD; cd17714; BRCT_PAXIP1_rpt1; 1.
DR   CDD; cd17710; BRCT_PAXIP1_rpt2; 1.
DR   CDD; cd17711; BRCT_PAXIP1_rpt3; 1.
DR   CDD; cd17730; BRCT_PAXIP1_rpt4; 1.
DR   CDD; cd17712; BRCT_PAXIP1_rpt5; 1.
DR   CDD; cd18440; BRCT_PAXIP1_rpt6; 1.
DR   Gene3D; 3.40.50.10190; BRCT domain; 5.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   PANTHER; PTHR23196; PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR23196:SF37; PAX-INTERACTING PROTEIN 1; 1.
DR   Pfam; PF00533; BRCT; 1.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF12738; PTCB-BRCT; 2.
DR   Pfam; PF16770; RTT107_BRCT_5; 1.
DR   SMART; SM00292; BRCT; 5.
DR   SUPFAM; SSF52113; BRCT domain; 5.
DR   PROSITE; PS50172; BRCT; 5.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT   DOMAIN          1..66
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          67..156
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          584..677
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          699..751
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          841..922
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   REGION          161..244
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          372..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          408..472
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          528..576
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..182
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..215
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        216..231
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        425..472
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        528..557
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        558..573
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1060 AA;  120631 MW;  F1DC4B5A0BDA1753 CRC64;
     VIQLLKAGKA KEVSYNALAS HIISEDGDNP EVGEAREVFD LPVVKPSWVI LSVQCGALLP
     VNGFSPESCQ IFFGITACLS QVSSEDRSAL WALVTFYGGD CQLTLNKKCT HLIVPEPKGE
     KYECALKRAS IKIVTPDWVL DCVSEKTKKD EAFYHPRLII YEEEEEEEEE EEEVENEEQD
     SQNEGSTDEK SSPASSQEGS PSGDQQFSPK SNTEKSKGEL MFDDSSDSSP EKQERNLNWT
     PAEVPQLAAA KRRLPQGKEP GLINLCANVP PVPGNILPPE VRGNLMAAGQ NLQSSERSEM
     IATWSPAVRT LRNITNNADI QQINRPSNVA HILQTLSAPT KNLEQQVNHS QQGHTNANAV
     LFSQVKVTPE THMLQQQQQA QQQQQQQHPV LHLQPQQIMQ LQQQQQQQQQ QQISQQPYPQ
     QPPHPFSQQQ QQQQQAHPHQ FSQQQLQFPQ QQLHPPQQLH RPQQQLQPFQ QQHALQQQFH
     QLQQHQLQQQ QLAQLQQQHS LLQQQQQQQQ QIQQQQLQQQ QLQRMHQQQQ MQSQTAPHLS
     QTSQALQHQV PSQQPPQQQH QQQPPPPPPQ HHQLFGHDPA VEIPEEGFLL GCVFAIADYP
     EQMSDKQLLA TWKRIIQAHG GTVDPTFTSR CTHLLCESQV SSVYAQAIRE RKRCITAHWL
     NTVLKKKKMV PPHRALHFPV AFPPGGKPCS HPRVPFVNDR DDLKLMAYLA GAKYTGYLCR
     SNTVLICKEP TGLKYEKAKE WRIPCVNAQW LGDILLGNFE ALRQIQYSRY TAFSLQDPFA
     PTQHLVLNLL ATVLLSRLIE LNVRLPPKLK QNEVANVQPS SKRARIEDIP PPTKKLTPEL
     TPFVLFTGFE PVQVQQYIKK LYILGGEVAE SAQKCTHLVA SKVTRTVKFL TAISVVKHIV
     TPEWLEECFR CQKFIDEQNY ILRDAEAEVL FSFSLEESLK RAHVSPLFKA KYFYITPGIC
     PSLSTMKAIV ECAGGKVLSK QPSFRKLMEH KQNSSLSEII LISCENDLHL CREYFARGID
     VHNAEFVLTG VLTQTLDYES YPFQKRIKSR WVGYEMDFPD
//