ID   A0A2K6BIS9_MACNE        Unreviewed;       739 AA.
AC   A0A2K6BIS9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Interleukin 17 receptor D {ECO:0000313|Ensembl:ENSMNEP00000011290.1};
GN   Name=IL17RD {ECO:0000313|Ensembl:ENSMNEP00000011290.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000011290.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000011290.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   RefSeq; XP_011741035.1; XM_011742733.1.
DR   AlphaFoldDB; A0A2K6BIS9; -.
DR   STRING; 9545.ENSMNEP00000011290; -.
DR   Ensembl; ENSMNET00000035473.1; ENSMNEP00000011290.1; ENSMNEG00000029993.1.
DR   GeneID; 105482558; -.
DR   KEGG; mni:105482558; -.
DR   CTD; 54756; -.
DR   GeneTree; ENSGT00940000156669; -.
DR   OrthoDB; 2950063at2759; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000029993; Expressed in adult mammalian kidney and 5 other cell types or tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0030368; F:interleukin-17 receptor activity; IEA:InterPro.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   Gene3D; 3.40.50.11530; -; 1.
DR   InterPro; IPR039465; IL-17_rcpt-like.
DR   InterPro; IPR031951; IL17R_D_N.
DR   InterPro; IPR013568; SEFIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR15583; INTERLEUKIN-17 RECEPTOR; 1.
DR   PANTHER; PTHR15583:SF14; INTERLEUKIN-17 RECEPTOR D; 1.
DR   Pfam; PF16742; IL17R_D_N; 1.
DR   Pfam; PF08357; SEFIR; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS51534; SEFIR; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..739
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014434696"
FT   DOMAIN          355..509
FT                   /note="SEFIR"
FT                   /evidence="ECO:0000259|PROSITE:PS51534"
FT   REGION          650..716
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        665..702
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   739 AA;  82434 MW;  BF4AB54451D7ED64 CRC64;
     MAPWLQLCSV FFTVNACLNG SQLAVAAGGS GRARGADTCG WRGVGPASRN SGLYNITFKY
     DNCTTYFNPV GKHVIADAQN ITISQYACHD QVAVTILWSP GALGIEFLKG FRVILEELKS
     EGRQCQQLIL KDPKQLNSSF KRTGMESQPF LNMKFETDYF VKVVPFPSIK NESNYHPFFF
     RTRACDLLLQ PDNLACKPFW KPRNLNISQH GSDMQVSFDH APHNFGFRFF YLHYKLKHEG
     PFKRKTCKQE QNTETTSCLL QNVSPGDYII ELMDDTNTTR KVMHYALKPV HSPWAGPIRA
     VAITVPLVVI SAFATLFTVM CRKKQQENIY SHLDEESSES STYTAALPRE RLRPRPKVFL
     CYSSKDGQNH MNVVQCFAYF LQDFCGCEVA LDLWEDFSLC REGQREWVIQ KIHESQFIIV
     VCSKGMKYFV DKKNYKHKGG GRGSGKGELF LVAVSAIAEK LRQAKQSSSA ALSKFIAVYF
     DYSCEGDVPG VLDLSTKYKL MDNLPQLCSH LHSRDHGLQE LGQHARQGSR RNYFRSKSGR
     SLYVAICNMH QFIDEEPDWF EKQFVPFHAP PLRYREPVLE KFDSGLVLND VMCKPGPESD
     FCLKVEAAVL GATGPADSQH ESQHGGLDQD VEARPALDGS AALQPLLHTV KAGSPSDMPR
     DSGIYDSSVP SSELSLPLME GLSTDQTETS SLTESVSSSS GLGEEEPPAL PSKLLSSGAC
     KADLGCRSYT DELHAVAPL
//