ID A0A2K6BJB9_MACNE Unreviewed; 619 AA.
AC A0A2K6BJB9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Autophagy related 16 like 1 {ECO:0000313|Ensembl:ENSMNEP00000011492.1};
GN Name=ATG16L1 {ECO:0000313|Ensembl:ENSMNEP00000011492.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000011492.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000011492.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat ATG16 family.
CC {ECO:0000256|ARBA:ARBA00009271}.
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DR AlphaFoldDB; A0A2K6BJB9; -.
DR Ensembl; ENSMNET00000035675.1; ENSMNEP00000011492.1; ENSMNEG00000030017.1.
DR GeneTree; ENSGT00940000153936; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000030017; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR CDD; cd22887; Atg16_CCD; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR045160; ATG16.
DR InterPro; IPR013923; Autophagy-rel_prot_16_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19878; AUTOPHAGY PROTEIN 16-LIKE; 1.
DR PANTHER; PTHR19878:SF6; AUTOPHAGY-RELATED PROTEIN 16-1; 1.
DR Pfam; PF08614; ATG16; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 16..206
FT /note="Autophagy-related protein 16"
FT /evidence="ECO:0000259|Pfam:PF08614"
FT REPEAT 330..363
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 374..415
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 416..457
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 474..496
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 552..583
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 585..619
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT COILED 82..230
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 619 AA; 69719 MW; 0AAAA60690D1D267 CRC64;
MSSGLRAADF PRWKRHISEE LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAQKLQAEK
HDVPNRHEIS PGHDGTWNDS QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQQK
DREMQMNEAK IAECLQTISD LETECLELRT KLCDLERANQ TLKDEYDALQ ITFTALEEKL
RKTTEENQEL VTRWMAEKAQ EANRLNAENE KDSRRRQARL QKELAEAAKE PLPVEQDDDI
EVIVDETSDH TEETSPVRAI SRAATKRLSQ PAGGLLDSIT NIFGPFLFKM CISIPKRRSV
SSFPVPQDNV DTHPGSGKEV RVPTTALCVF DAHDGEVNAV QFSPGSRLLA TGGMDRRVKL
WEVFGEKCEF KGSLSGSNAG ITSIEFDSAG SYLLAASNDF ASRIWTVDDY RLRHTLTGHS
GKVLSAKFLL DNARIVSGSH DRTLKLWDLR SKVCIKTVFA GSSCNDIVCT EQCVMSGHFD
KKIRFWDIRS ESIVREMELL GKITALDLNP ERTELLSCSR DDLLKVIDLR TNAVKQTFSA
PGFKCGSDWT RVVFSPDGSY VAAGSAEGSL YIWSVLTGKV EKVLSKQHSS SINAVAWSPS
GSHVVSVDKG CKAVLWAQY
//
