ID A0A2K6BL38_MACNE Unreviewed; 292 AA.
AC A0A2K6BL38;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Lymphotoxin beta receptor {ECO:0000313|Ensembl:ENSMNEP00000012112.1};
GN Name=LTBR {ECO:0000313|Ensembl:ENSMNEP00000012112.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000012112.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000012112.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR AlphaFoldDB; A0A2K6BL38; -.
DR Ensembl; ENSMNET00000036306.1; ENSMNEP00000012112.1; ENSMNEG00000030358.1.
DR GeneTree; ENSGT00940000162178; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000030358; Expressed in liver and 12 other cell types or tissues.
DR GO; GO:0048534; P:hematopoietic or lymphoid organ development; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0043123; P:positive regulation of canonical NF-kappaB signal transduction; IEA:InterPro.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR017349; TNFR_3_LTBR.
DR PANTHER; PTHR47607; TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 3; 1.
DR PANTHER; PTHR47607:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 3; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR PRINTS; PR01920; TNFACTORR3.
DR SMART; SM00208; TNFR; 2.
DR SUPFAM; SSF57586; TNF receptor-like; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 62..103
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 62..103
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT REGION 93..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..253
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 63..78
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 292 AA; 30865 MW; A16C517BA69219C8 CRC64;
MGLEEIAPCT SKRKTQCRCQ PGMFCAAWAL ECTHCELLSD CPPGTEAELK DEVGKGNNHC
VPCKAGHFQN TSSPRARCQP HTRCEDQGLV EAAPGTAQSD TTCRNPSESL PPEMSGSLLK
RRPQGEGPNP VAAGWDPPKA NPQYPDLVEP LLPISGDVSP VSTGLPTALV SEEGVPQQQS
PLDLTREPQL EPGEQNQVAH GTNGIHVTGG SMTITGNIYI YNGPVLGGPP GPGDLPATPD
PPYPIPEEGD PGPPGLSTPH QEDGKAWHLA ETEHCGATPS NRGPRSQFIT YD
//
