ID A0A2K6BPM5_MACNE Unreviewed; 451 AA.
AC A0A2K6BPM5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Sorting nexin 7 {ECO:0000313|Ensembl:ENSMNEP00000013322.1};
GN Name=SNX7 {ECO:0000313|Ensembl:ENSMNEP00000013322.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000013322.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000013322.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Heterodimer; heterodimerizes with SNX4.
CC {ECO:0000256|ARBA:ARBA00038663}.
CC -!- SUBCELLULAR LOCATION: Early endosome membrane
CC {ECO:0000256|ARBA:ARBA00004469}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004469}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004469}. Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004125}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004125}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004125}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR AlphaFoldDB; A0A2K6BPM5; -.
DR STRING; 9545.ENSMNEP00000013322; -.
DR Ensembl; ENSMNET00000037522.1; ENSMNEP00000013322.1; ENSMNEG00000030917.1.
DR GeneTree; ENSGT00940000155315; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000030917; Expressed in pituitary gland and 12 other cell types or tissues.
DR GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:2000786; P:positive regulation of autophagosome assembly; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd07666; BAR_SNX7; 1.
DR CDD; cd07284; PX_SNX7; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR042131; BAR_SNX7.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR042130; PX_SNX7.
DR PANTHER; PTHR45949; SORTING NEXIN-4; 1.
DR PANTHER; PTHR45949:SF3; SORTING NEXIN-7; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 94..215
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 51711 MW; 87F3954B861CB49B CRC64;
MEGERRASQA RSSGLPAGGA DGESPGGSAP FPGSSGSSAL LQAEVLDLDE DEDDLEVFSK
DASLMDMNSF SPMMPTSPLS MINQIKFEDE PDLKDLFITV DEPESHVTTI ETFITYRIIT
KTSRGEFDSS EFEVRRRYQD FLWLKGKLEE AHPTLIIPPL PEKFIVKGMV ERFNDDFIET
RRKALHKFLN RIADHPTLTF NEDFKIFLTA QAWELSSHKK QGPGLLSRMG QTVRAVASSM
RGVKNRPEEF MEMNNFIELF SQKINLIDKI SQRIYKEERE YFDEMKEYGP IHILWSASEE
DLVDTLKDVA GCIDRCCKAT EKRMSGLSEA LLPVVHEYVL YSEMLMGVMK RRDQIQAELD
SKVEALTYKK TDTDLLPEEI GKLEDKVECA NNALKADWER WKQNMQNDIK LAFTDMAEEN
IHYYEQCLAT WESFLTSQTN LHLEETSEDK P
//
