ID   A0A2K6BQQ2_MACNE        Unreviewed;       285 AA.
AC   A0A2K6BQQ2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=ADAM metallopeptidase domain 17 {ECO:0000313|Ensembl:ENSMNEP00000013707.1};
GN   Name=ADAM17 {ECO:0000313|Ensembl:ENSMNEP00000013707.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000013707.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000013707.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR   AlphaFoldDB; A0A2K6BQQ2; -.
DR   Ensembl; ENSMNET00000037909.1; ENSMNEP00000013707.1; ENSMNEG00000031025.1.
DR   GeneTree; ENSGT00940000155443; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000031025; Expressed in lung and 12 other cell types or tissues.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   PANTHER; PTHR45702; ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR45702:SF6; DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..285
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014333646"
SQ   SEQUENCE   285 AA;  33190 MW;  41CD93167AE8C3B4 CRC64;
     MRQCLLFLTS VVPFVLAPRP PDDPSFGPHQ RLEKLDSLLS DYDILSLSNI QQHSVRKRDL
     QTSTHVETLL TFSALKRHFK LYLTSSTERF SQNFKVVVVD GKNESEYTVK WQDFFTGHMV
     GEPDSRVLAH IRDDDVMIRI NTDGAEYNIE PLWRFVNDTK DKRMLVYKSE DIKNVSRLQS
     PKVCGYLKVD NEELLPKGLV DRGPPEELVH RVKRRADPDP MKNTCKLLVV ADHRFYRYMG
     RGEESTTTNY LIELIDRVDD IYRNTSWDNA GFKGYGIQIE QLLFE
//