GenomeNet

Database: UniProt
Entry: A0A2K6C0Z8_MACNE
LinkDB: A0A2K6C0Z8_MACNE
Original site: A0A2K6C0Z8_MACNE 
ID   A0A2K6C0Z8_MACNE        Unreviewed;       232 AA.
AC   A0A2K6C0Z8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=KxDL motif-containing protein 1 {ECO:0000256|ARBA:ARBA00014719};
DE   AltName: Full=Ubiquitin A-52 residue ribosomal protein fusion product 1 {ECO:0000256|ARBA:ARBA00032326};
DE   AltName: Full=Ubiquitin-ribosomal protein eL40 fusion protein {ECO:0000256|ARBA:ARBA00035298};
GN   Name=UBA52 {ECO:0000313|Ensembl:ENSMNEP00000017349.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000017349.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000017349.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Component of the 60S subunit of the ribosome.
CC       {ECO:0000256|ARBA:ARBA00002241}.
CC   -!- SUBUNIT: Part of the 60S ribosomal subunit.
CC       {ECO:0000256|ARBA:ARBA00035124}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the KXD1 family.
CC       {ECO:0000256|ARBA:ARBA00005913}.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the eukaryotic
CC       ribosomal protein eL40 family. {ECO:0000256|ARBA:ARBA00010570}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the ubiquitin family.
CC       {ECO:0000256|ARBA:ARBA00008373}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K6C0Z8; -.
DR   STRING; 9545.ENSMNEP00000017349; -.
DR   Ensembl; ENSMNET00000041575.1; ENSMNEP00000017349.1; ENSMNEG00000032643.1.
DR   GeneTree; ENSGT00940000153593; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000032643; Expressed in lymph node and 12 other cell types or tissues.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd01803; Ubl_ubiquitin; 1.
DR   Gene3D; 4.10.1060.50; -; 1.
DR   InterPro; IPR039843; KXD1-like.
DR   InterPro; IPR019371; KxDL_dom.
DR   InterPro; IPR001975; Ribosomal_eL40_dom.
DR   InterPro; IPR038587; Ribosomal_eL40_sf.
DR   InterPro; IPR011332; Ribosomal_zn-bd.
DR   InterPro; IPR000626; Ubiquitin-like_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR019954; Ubiquitin_CS.
DR   InterPro; IPR019956; Ubiquitin_dom.
DR   PANTHER; PTHR13511:SF0; KXDL MOTIF-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR13511; UNCHARACTERIZED; 1.
DR   Pfam; PF10241; KxDL; 1.
DR   Pfam; PF01020; Ribosomal_L40e; 1.
DR   Pfam; PF00240; ubiquitin; 1.
DR   PRINTS; PR00348; UBIQUITIN.
DR   SMART; SM01377; Ribosomal_L40e; 1.
DR   SMART; SM00213; UBQ; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   SUPFAM; SSF57829; Zn-binding ribosomal proteins; 1.
DR   PROSITE; PS00299; UBIQUITIN_1; 1.
DR   PROSITE; PS50053; UBIQUITIN_2; 1.
PE   3: Inferred from homology;
KW   ADP-ribosylation {ECO:0000256|ARBA:ARBA00022765};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW   Ribosomal protein {ECO:0000256|ARBA:ARBA00022980}.
FT   DOMAIN          105..180
FT                   /note="Ubiquitin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50053"
SQ   SEQUENCE   232 AA;  26802 MW;  4A6E8ED6D5C8C888 CRC64;
     MDLPDSASRV FCGRILSMVN TDDVNAIILA QKNMLDRFEK TNEMLLNFNN LSSARLQQMS
     ERFLHHTRTL VEMKRDLDSI FRRIRTLKGK LARQHPEAFS PDANMQIFVK TLTGKTITLE
     VEPSDTIENV KAKIQDKEGI PPDQQRLIFA GKQLEDGRTL SDYNIQKEST LHLVLRLRGG
     IIEPSLRQLA QKYNCDKMIC RKCYARLHPR AVNCRKKKCG HTNNLRPKKK VK
//
DBGET integrated database retrieval system