ID A0A2K6C3Z4_MACNE Unreviewed; 761 AA.
AC A0A2K6C3Z4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Zinc finger protein 287 {ECO:0000313|Ensembl:ENSMNEP00000018387.1};
GN Name=ZNF287 {ECO:0000313|Ensembl:ENSMNEP00000018387.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000018387.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000018387.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR RefSeq; XP_011716679.1; XM_011718377.1.
DR RefSeq; XP_011716680.1; XM_011718378.1.
DR RefSeq; XP_011716681.1; XM_011718379.1.
DR SMR; A0A2K6C3Z4; -.
DR STRING; 9545.ENSMNEP00000018396; -.
DR Ensembl; ENSMNET00000042622.1; ENSMNEP00000018387.1; ENSMNEG00000033114.1.
DR Ensembl; ENSMNET00000042631.1; ENSMNEP00000018396.1; ENSMNEG00000033114.1.
DR GeneID; 105468298; -.
DR KEGG; mni:105468298; -.
DR CTD; 57336; -.
DR GeneTree; ENSGT00940000162333; -.
DR OrthoDB; 4625041at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000033114; Expressed in cerebellum and 12 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR CDD; cd07936; SCAN; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 14.
DR Gene3D; 1.10.4020.10; DNA breaking-rejoining enzymes; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR003309; SCAN_dom.
DR InterPro; IPR038269; SCAN_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24393:SF168; FI01120P-RELATED; 1.
DR PANTHER; PTHR24393; ZINC FINGER PROTEIN; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF02023; SCAN; 1.
DR Pfam; PF00096; zf-C2H2; 14.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00431; SCAN; 1.
DR SMART; SM00355; ZnF_C2H2; 14.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 8.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR SUPFAM; SSF47353; Retrovirus capsid dimerization domain-like; 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS50804; SCAN_BOX; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 14.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 14.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 49..127
FT /note="SCAN box"
FT /evidence="ECO:0000259|PROSITE:PS50804"
FT DOMAIN 170..238
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 368..395
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 396..423
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 424..451
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 452..479
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 480..507
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 508..535
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 536..563
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 564..591
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 592..619
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 620..647
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 648..675
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 676..703
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 704..731
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 732..759
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 134..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 761 AA; 88330 MW; 747A70054910931B CRC64;
MLASSKRMNN SSRSQILLRW KSDKAQSGPY NVEKEILTSR FLRDTETCRQ NFRNFPYPDL
AGPRKALSQL RELCLKWLRP EIHSKEQILE LLVLEQFLTI LPGEVRTWVK SQYPESSEEA
VTLVEDLTQI LEEEAPQNST LSQDTPEEDP RGKHAFQAGW LNDLVTKESM TFKDVAVDIT
QEDWELMRPV QKELYKTVTL QNYWNMVSLG LTVYRPTVIP MLEEPWMVIK EILEGPSPEW
ETKVQACTPV ENMSKLTKEE TQTIKLEDSY DYNDRLQRRA TGGFWKFHTN ERGFSLKSVL
SQEDDPTEEC LSKYDIYRNN FEKHSNLIVQ FDTQLDNKTS VYNEGRATFN HVSYGIVHRK
ILPGEKPYKC NVCGKKFRKY PSLLKHQSTH AKEKSYECEE CGKEFRHISS LIAHQRMHTG
EKPYECHQCG KAFSQRAHLT IHQRIHTGEK PYKCDDCGKD FSQRAHLTIH QRTHTGEKPY
KCLECGKTFS HSSSLINHQR VHTGEKPYIC NECGKTFSQS THLLQHQKIH TGKKPYKCNE
CWKVFSQSTY LIRHQRIHSG EKCYKCNECG KAFAHSSTLI QHQTTHTGEK SYICNICGKA
FSQSANLTQH HRTHTGEKPY KCSVCGKAFS QSVHLTQHQR IHNGEKPFKC NICGKAYRQG
ANLTQHQRIH TGEKPYKCNE CGKAFIYSSS LNQHQRTHTG ERPYKCNECD KDFSQRTCLI
QHQRIHTGEK PYACRTCGKT FTQSTNLIQH QRVHTGAKHR N
//
