ID   A0A2K6C9Q2_MACNE        Unreviewed;        88 AA.
AC   A0A2K6C9Q2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Pyrin domain containing 1 {ECO:0000313|Ensembl:ENSMNEP00000020381.1};
GN   Name=PYDC1 {ECO:0000313|Ensembl:ENSMNEP00000020381.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000020381.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000020381.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K6C9Q2; -.
DR   STRING; 9545.ENSMNEP00000020381; -.
DR   Ensembl; ENSMNET00000044628.1; ENSMNEP00000020381.1; ENSMNEG00000034009.1.
DR   GeneTree; ENSGT00940000164730; -.
DR   OMA; QLVASYY; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000034009; Expressed in skeletal muscle tissue and 1 other cell type or tissue.
DR   GO; GO:0008385; C:IkappaB kinase complex; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IEA:Ensembl.
DR   GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0032731; P:positive regulation of interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IEA:Ensembl.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR004020; DAPIN.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   Pfam; PF02758; PYRIN; 1.
DR   SMART; SM01289; PYRIN; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50824; DAPIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT   DOMAIN          6..88
FT                   /note="Pyrin"
FT                   /evidence="ECO:0000259|PROSITE:PS50824"
SQ   SEQUENCE   88 AA;  9898 MW;  14F0E6A2A11D3899 CRC64;
     VEGQREVLEN LTRTEPEKFK MGRMKLGTVP LREGFERIPR GALGQLDIVD LTDQLVASYY
     EDYAVEFVVA VLLDMGMLEE AAQLPRAA
//