ID A0A2K6CGW9_MACNE Unreviewed; 730 AA.
AC A0A2K6CGW9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Synaptotagmin like 5 {ECO:0000313|Ensembl:ENSMNEP00000022912.1};
GN Name=SYTL5 {ECO:0000313|Ensembl:ENSMNEP00000022912.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000022912.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000022912.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011708560.1; XM_011710258.1.
DR AlphaFoldDB; A0A2K6CGW9; -.
DR Ensembl; ENSMNET00000047172.1; ENSMNEP00000022912.1; ENSMNEG00000035074.1.
DR GeneID; 105463245; -.
DR CTD; 94122; -.
DR GeneTree; ENSGT00940000158618; -.
DR OrthoDB; 590187at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000035074; Expressed in lung and 3 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd04029; C2A_SLP-4_5; 1.
DR CDD; cd04020; C2B_SLP_1-2-3-4; 1.
DR CDD; cd15766; FYVE_Slp5; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR041282; FYVE_2.
DR InterPro; IPR010911; Rab_BD.
DR InterPro; IPR037303; SLP-4/5_C2A.
DR InterPro; IPR043567; SYTL1-5_C2B.
DR InterPro; IPR042783; SYTL5_FYVE.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45716; BITESIZE, ISOFORM I; 1.
DR PANTHER; PTHR45716:SF6; SYNAPTOTAGMIN-LIKE PROTEIN 5; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF02318; FYVE_2; 1.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS50916; RABBD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 7..123
FT /note="RabBD"
FT /evidence="ECO:0000259|PROSITE:PS50916"
FT DOMAIN 406..527
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 563..694
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 147..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 32..59
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 148..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..186
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..323
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 81470 MW; D3ECA905410395C5 CRC64;
MSKNSEFINL SFLLDHEKEM ILGVLKRDEY LKKVEDKRIR KLKNELLEAK RRSGKTQQEA
SRVCVHCQRN LGLIFDRGDP CQSCSLRVCR ECRVAGPDGS WKCTVCDKIA QLRIITGEWF
FEEKAKRFKQ VNVLGTDVVR QSILRRSPGA EEVQSQEQTC QDAEKSDTSP VAGKKASHDG
PKRKGFLLSK FRSATRGEII TPKTQSGRSY SLDLDGQHFR SLKSAPGSDR GSTGSSDLND
QEAGSRTPKS SRSSGVTPVT QRSPAPSTRS VTSVISREYG FENSTDLAAL EGTSQEFTKS
HRRNTSGTPS IAVSGTSLSS DRSRSELDLS ESFTEDLEDT VSIRSKSVPG TLDKDSLEET
EESIDALVSS QLSTNTHSLA SGLSTTSLNS MMSVYSETGD YGNVKVSGEI LLHISYCYKT
GGLYILVKNC RNLAIGDEKK QRTDAYVKSY LLPDKSRNNK RKTKIRTGTN PEFNETLKYT
ISHTQLETRT LQLSVWHYDR FGRNSFLGEV EIPFDSWNFE NPTDEWFVLQ PKVEFAPDIG
LQYKGELTVV LRYIPPEENL MLPPEQLQGN KTFKKGKKKE SPVISGGILE VFIKEAKNLT
AVKSGGTSDS FVKGYLLPDD SKATKHKTLV IKKSVNPQWN HTFMFSGIHP QDIKNVCLEL
TIWDKEAFSS NIFLGGVRLN SGSGVSHGKN VDWMDSQGEE QRLWQKMANN PGTPFEGVLM
LRSSMGKCRL
//
