ID A0A2K6CJ71_MACNE Unreviewed; 1722 AA.
AC A0A2K6CJ71;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Lymphocyte antigen 75 {ECO:0000313|Ensembl:ENSMNEP00000023697.1};
GN Name=LY75 {ECO:0000313|Ensembl:ENSMNEP00000023697.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000023697.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000023697.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00479}.
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DR RefSeq; XP_011758965.1; XM_011760663.1.
DR STRING; 9545.ENSMNEP00000023697; -.
DR Ensembl; ENSMNET00000047963.1; ENSMNEP00000023697.1; ENSMNEG00000035436.1.
DR GeneID; 105493182; -.
DR KEGG; mni:105493182; -.
DR CTD; 4065; -.
DR GeneTree; ENSGT01050000244842; -.
DR OMA; MITKNRH; -.
DR OrthoDB; 4271106at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000035436; Expressed in thymus and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00037; CLECT; 10.
DR CDD; cd00062; FN2; 1.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 10.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR22803:SF65; LYMPHOCYTE ANTIGEN 75; 1.
DR PANTHER; PTHR22803; MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED; 1.
DR Pfam; PF00040; fn2; 1.
DR Pfam; PF00059; Lectin_C; 10.
DR SMART; SM00034; CLECT; 10.
DR SMART; SM00059; FN2; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 10.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 10.
DR PROSITE; PS00023; FN2_1; 1.
DR PROSITE; PS51092; FN2_2; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Lectin {ECO:0000256|ARBA:ARBA00022734};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..1722
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014379195"
FT TRANSMEM 1667..1691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 164..211
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 225..341
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 368..486
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 507..614
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 652..763
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 818..931
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 958..1083
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1110..1212
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1251..1359
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1401..1503
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1542..1651
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
SQ SEQUENCE 1722 AA; 198510 MW; E2A754297D46AE02 CRC64;
MRTDWATPRR PAGLLMLLLW CFELAEPSGR AANDPFTIVH GNTGKCIKPV YGWIVAEDCD
ETEDKLWKWV SQHRLFHLHS QKCLGLDITK SVNEVRMFSC DSSVMLWWKC EHHSLYSAAR
YQLALKNGHG AAISNASDIW KKGGSEESLC DQPYHEIYTR DGNSYGRPCE FPFLVDGTWH
HDCILDEDHS GPWCATTSNY EYDRKWGICL KPENGCEDNW EKNEQFGSCY QFNTQTALSW
KEAYVSCQNQ GADLLSINSA AELTYLKEKE GIAKIFWIGL NQLYSARGWE WSDHKPLNFL
NWDPDRPSAP TIGGSSCARM DAESGLWQSF SCDAQLPYVC RKPLNNTVEL TDVWTYSDTR
CDAGWLPNNG FCYLLVNESN SWDKAHAKCK DFSGDLISIH SLADVEVVVT KLHNEDTKEE
VWIGLKNINI PTLFQWSDGT EVTLTYWDEN EPNVPYNKTP NCVSYLGELG QWKVQLCEEK
LKYVCKRKGE KLNDTSSDKM CPPNEGWKRH GETCYKIYED EVPFGTNCNL TITSRFEQEY
LNDLMKKYDK SLRKYFWTGL RDVDSRGEYN WATVGGTRRS VTFSNWNFLE PASPGGCVAM
STGKSLGKWE VKDCRSFKAL SICKKMSGPL EPEEAAPKPD DPCPEGWQSF PTSLSCYKVF
HAERIVRKRN WEEAERFCQA LGAHLSSFSR VDEIKEFLHF LTDQFSGQRW LWIGLNKRSP
DLQGSWQWSD RTPVSTIIMP NEFQQDYDIR DCAAVKVFHR PWRRGWHFYD DREFIYLRPF
ACDTKLEWVC QIPKGRTPKT PDWYNPERAG VHGPPLIIEG SEYWFVADLH LNYEEAVLYC
ASNHSFLATI TSFAGLKAIK NKIANISGDG QKWWIRINEQ PIDDHFTYSR YPWHHFHVTF
GEECLYMSAK TWLIDLSKPT DCNTKLPFIC EKYNVSSLEK YSPDSAAKVQ CSEQWIPFQN
KCFLKIKPMS LTFSQASDTC HSYGGTLPSV LSQIEQDFIT SLLPDMEATL WIGLRWTAYE
RINKWTDNRE LTYSNFHPLL VSRRLRIPEN LFEEESHYHC ALILNLQKSP FIGTWNFTSC
SERHFVSLCQ KYSEVKGRQT LQNASETVKY LNNLYKIIPK TLTWHGAQKE CLKNNMQLVS
ITDPYQQAFL SVQALLHNSS LWIGLFSQDD ELNFGWSDGK RLHFSRWAET NGQLEDCVIL
DTDGFWKTAD CNDNQPGAIC YYSGNETEKE VKPVDSVKCP SPVLNTPWIP FQNCCYNFII
TKNRHMATTL DEVHSKCQKL NPKSQILSIR DEKENNFVLE QLLYFNYMAS WVTLGITYEN
NSFMWFDKTP LSYTHWRAGR PTIKNEKFLA GLSTDGFWDI KTFNVIEETL YFHQHSILAC
KIEMVDYKEE YNTTLPQFMP YEDGIYSVIQ KKVTWYEALN MCSQSGGHLA SVHDQNGQLF
LEDIVKRDGF PLWVGLSSHD GSESSFEWSD GSIFDYIPWK GQTSPGNCVL LDPKGTWKHE
KCNSLKDGAI CYKPTKSKKL SHLTYSSRCP TVKENGSRWI QYKGHCYTSD QALHSFSEAK
KLCSKHDQSA TIVSIKDEDE NKFVSRLMRE NNNITMRVWL GLSQHSVDQS WSWLDGSEVT
FVKWENKSKS GIGKCSMLIA SNETWKNVEC EHGFGRVVCK MPLGPDYTSI AIAVATLSIL
VLMGVLIWFV FQRHRLHLAG FSAVRYAQGV NEDEIMLPSF HD
//
