ID A0A2K6CJA8_MACNE Unreviewed; 558 AA.
AC A0A2K6CJA8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Zinc finger protein 430 {ECO:0008006|Google:ProtNLM};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000023744.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000023744.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR AlphaFoldDB; A0A2K6CJA8; -.
DR Ensembl; ENSMNET00000048010.1; ENSMNEP00000023744.1; ENSMNEG00000035467.1.
DR GeneTree; ENSGT01100000263507; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000035467; Expressed in thymus and 12 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 13.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR16515; PR DOMAIN ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR16515:SF55; ZINC FINGER PROTEIN 711; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 11.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 12.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 11.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 12.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 23..95
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 193..220
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 221..248
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 249..276
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 277..304
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 305..332
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 333..360
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 361..388
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 389..416
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 417..444
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 445..472
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 473..500
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 501..528
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 558 AA; 65077 MW; 4B29BFFAB0A54FE3 CRC64;
MGWMAAQNHL QMPSKQIQKR GPLTFRDVAI EFSLEEWQCL DTAQQDLYRK VMLENYRNLV
FLAGIAVSNP DLITCLEQGK EPWNMKRHVM ADEPPVIYSH FAQDLWPEQG IKDSFQEVIL
RRYGKGGHED LQLRTDCKSV DECNLHKECY NELNQCLTTT QSEIFQCDKY VNVFYTFSNS
NIHKIRHTGK KPFKCKKCDK SFCMLLHLTQ HKRIHIRENS YQCEECGKVF NWFSTLTRHR
RIHTGEKPYK CEECGKAFKQ SSTLTTHKII HTGEKPYRCE ECGKTFNRSS HLTTHKRIHT
GEKPYRCEEC GRAFNRSSHL TTHKIIHTGE KPYKCEECGK AFNQSSTLTT HKIIHAGEKP
YKCEECGKAF YRFSYLTKHK IIHTGEKFYK CEECGKGFNW SSTLTKHKRI HTGEKPYKCE
QCGKAFNESS NLTAHKIIHT GEKPYKCEEC GKAFNRSPKL TAHKVIHSGE KPYKCEKCGK
AFNQFSNLTK HKITHIGDTS YTYLECDKAF SQSSTLTKHK VIHTGEKPYN CEEYSKTFNQ
SSNLIEQSNS YWRETLQM
//
