ID A0A2K6CKZ9_MACNE Unreviewed; 453 AA.
AC A0A2K6CKZ9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Ankyrin repeat and SOCS box containing 16 {ECO:0000313|Ensembl:ENSMNEP00000024317.1};
GN Name=ASB16 {ECO:0000313|Ensembl:ENSMNEP00000024317.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000024317.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000024317.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
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DR RefSeq; XP_011718305.1; XM_011720003.1.
DR AlphaFoldDB; A0A2K6CKZ9; -.
DR STRING; 9545.ENSMNEP00000024317; -.
DR Ensembl; ENSMNET00000048584.1; ENSMNEP00000024317.1; ENSMNEG00000035701.1.
DR GeneID; 105469218; -.
DR KEGG; mni:105469218; -.
DR CTD; 92591; -.
DR GeneTree; ENSGT00940000160773; -.
DR OMA; PEMLKYC; -.
DR OrthoDB; 1787271at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000035701; Expressed in skeletal muscle tissue and 2 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03716; SOCS_ASB_like; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24171; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00248; ANK; 8.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 142..174
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 175..207
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 209..241
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 283..315
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 406..444
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 453 AA; 49738 MW; 79CCF8994FF5CD7D CRC64;
MARETFPFTS STLRSLRLQR EWLEWEDRRR AAAQQCRSRR CPSSPQARLT RPHRSCRDPA
VHHALFSGDL QQVQALFQDE EAANMIVETV SNQLAWSAEQ GFWVLTPKTK QTAPLAIATA
RGYTDCARHL IRQGAELDAR VGGRTALHEA CARAQLDCVR LLLTFGAKAN VLTEEGMTPL
HLCTIPESLQ CAKLLLEAGA TVNLAAGESQ ETPLHVAAAR GLEQHVALYL EHGADVGLRT
SQGETALNAA CAGAEGPGSC RRHQVAARRL LEAGADARAA GRKRHTPLHN ACANGCGGLA
ELLLRHGARA EVPNGAGHTP MDCALQAVQD APNWEPEVLF AALLDYGAQP VRPEMLKHCA
NFPRALEVLL NAYPCVPSCE TWVEAVLPEL WKEHEAFYSS ALCMVNQPRR LQHLARLAVR
ARLGSRCRQD ATRLPLPPLL RDYLLLRVEG RIQ
//
