ID A0A2K6CM96_MACNE Unreviewed; 928 AA.
AC A0A2K6CM96;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=EMAP like 3 {ECO:0000313|Ensembl:ENSMNEP00000024772.1};
GN Name=EML3 {ECO:0000313|Ensembl:ENSMNEP00000024772.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000024772.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000024772.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC {ECO:0000256|ARBA:ARBA00006489}.
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DR AlphaFoldDB; A0A2K6CM96; -.
DR STRING; 9545.ENSMNEP00000024772; -.
DR Ensembl; ENSMNET00000049042.1; ENSMNEP00000024772.1; ENSMNEG00000035836.1.
DR GeneTree; ENSGT00940000159589; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000035836; Expressed in lymph node and 12 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:1990498; C:mitotic spindle microtubule; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0043621; F:protein self-association; IEA:Ensembl.
DR GO; GO:0007080; P:mitotic metaphase chromosome alignment; IEA:Ensembl.
DR GO; GO:1901673; P:regulation of mitotic spindle assembly; IEA:Ensembl.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR005108; HELP.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF15; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 3; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF03451; HELP; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 217..285
FT /note="HELP"
FT /evidence="ECO:0000259|Pfam:PF03451"
FT REPEAT 601..633
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 745..778
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 51..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 16..43
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 78..93
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 928 AA; 98785 MW; 3FBA19E7029A6B12 CRC64;
MDGAAGPGEG PAREALQSLS QRLRVQEQEM ELVKAALAEA LRLLRLQVPP SSLQVSGTPA
PPGDSFAAPP GLPPTCTPSL VSRGTQTETE VEFKTSPGPP GLSNGPPAPQ GASEEPSGTQ
SEGGGSSSSG AGSPGPPGIL RPLQPPQRAD TPRRNSSSSS SPSERPRQKL SRKAISSANL
LVRSGSTESR GGKDPLSSPG GPGSRRSNYN LEGISVKMFL RGRPITMYIP SGIRSLEELP
SGPPPETLCL DWVYGYRGRD SRSNLFVLRS GEVVYFIACV VVLYRPGGGP GGPGGGGQRH
YRGHTDCLPC CSASLEKVLA VHPDGVRVAS GQTAGVDKDG KPLQPVVHIW DSETLLKLQE
IGLGAFERGV GALAFSAADQ GAFLCVVDDS NEHMLSVWDC SRGVKLAEIK STNDSVLAVG
FNPRDSSCIV TSGKSHVHFW NWSGGVGVPG NGTLTRKQGV FGKYKKPKFI PCFVFLPDGD
ILTGDSEGNI LTWGRSASDS KTPGRGGAKE TYGIVAQAHA HEGSIFALCL QRDGTVLSGG
GRDRRLVQWG PGLVALQEAE IPEHFGAVRA IAEGLGSELL VGTTKNALLR GDLAQGFSPV
IQGHTDELWG LCTHPSQNRF LTCGHDRQLC LWDGESHALA WSIDLKETGL CADFHPSGAV
VAVGLNTGRW LVLDTETREI VSDVIDGNEQ LSVVRYSPGG SHPNPGLTCM GCTWPLVPMT
TGLMHQGGSG DGKWMGYFKT LDLCSQGHSS FITHLDWSKD GNFIMSNSGD YEILYWDVAG
GCKQLKNRYE SRDREWATYT CVLGFHVYGE QGRAEPHVRG PRQPRDQRPV HARRLAPRLA
GRQGRQHLPV ASAGRWGRGA GACHALSNPL PVPRLLPRRL IAAGRTYWPG GVAPPRSAPG
RLFPRLTSKH SRRCISLEGA NGAPAHTV
//
