ID A0A2K6CME2_MACNE Unreviewed; 306 AA.
AC A0A2K6CME2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=NCK adaptor protein 1 {ECO:0000313|Ensembl:ENSMNEP00000024817.1};
GN Name=NCK1 {ECO:0000313|Ensembl:ENSMNEP00000024817.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000024817.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000024817.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6CME2; -.
DR Ensembl; ENSMNET00000049087.1; ENSMNEP00000024817.1; ENSMNEG00000035916.1.
DR GeneTree; ENSGT00940000156601; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000035916; Expressed in lymph node and 12 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR CDD; cd10408; SH2_Nck1; 1.
DR CDD; cd11901; SH3_Nck1_2; 1.
DR CDD; cd11904; SH3_Nck1_3; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR017304; NCK.
DR InterPro; IPR035882; Nck1_SH2.
DR InterPro; IPR035564; Nck1_SH3_2.
DR InterPro; IPR035565; Nck1_SH3_3.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR19969:SF16; CYTOPLASMIC PROTEIN NCK1; 1.
DR PANTHER; PTHR19969; SH2-SH3 ADAPTOR PROTEIN-RELATED; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF00018; SH3_1; 2.
DR PIRSF; PIRSF037874; Cytoplasmic_NCK; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00401; SH2DOMAIN.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 35..94
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 119..181
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 211..305
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
SQ SEQUENCE 306 AA; 34625 MW; AB273324534955F4 CRC64;
LDFIRIGKVK RKPSVPDSAS PADDSFVDPG ERLYDLNMPA YVKFNYMAER EDELSLIKGT
KVIVMEKCSD GWWRGSYNGQ VGWFPSNYVT EEGDSPLGDH VGSLSEKLAA VVNNLNTGQV
LHVVQALYPF SSSNDEELNF EKGDVMDVIE KPENDPEWWK CRKINGMVGL VPKNYVTVMQ
NNPLTSGLEP SPPQCDYIRP SLTGKFAGNP WYYGKVTRHQ AEMALNERGH EGDFLIRDSE
SSPNDFSVSL KAQGKNKHFK VQLKETVYCI GQRKFSTMEE LVEHYKKAPI FTSEQGEKLY
LVKHLS
//
