ID   A0A2K6CNU5_MACNE        Unreviewed;       471 AA.
AC   A0A2K6CNU5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Myocyte enhancer factor 2C {ECO:0000313|Ensembl:ENSMNEP00000025340.1};
GN   Name=MEF2C {ECO:0000313|Ensembl:ENSMNEP00000025340.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000025340.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000025340.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_011756991.1; XM_011758689.1.
DR   RefSeq; XP_011756992.1; XM_011758690.1.
DR   RefSeq; XP_011756993.1; XM_011758691.1.
DR   RefSeq; XP_011756994.1; XM_011758692.1.
DR   RefSeq; XP_011756995.1; XM_011758693.1.
DR   AlphaFoldDB; A0A2K6CNU5; -.
DR   SMR; A0A2K6CNU5; -.
DR   Ensembl; ENSMNET00000049615.1; ENSMNEP00000025340.1; ENSMNEG00000035741.1.
DR   GeneID; 105491929; -.
DR   CTD; 4208; -.
DR   GeneTree; ENSGT00940000157492; -.
DR   OrthoDB; 448298at2759; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000035741; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:UniProt.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd00265; MADS_MEF2_like; 1.
DR   Gene3D; 3.40.1810.10; Transcription factor, MADS-box; 1.
DR   InterPro; IPR022102; HJURP_C.
DR   InterPro; IPR033896; MADS_MEF2-like.
DR   InterPro; IPR002100; TF_MADSbox.
DR   InterPro; IPR036879; TF_MADSbox_sf.
DR   PANTHER; PTHR11945; MADS BOX PROTEIN; 1.
DR   PANTHER; PTHR11945:SF145; MYOCYTE-SPECIFIC ENHANCER FACTOR 2C; 1.
DR   Pfam; PF12347; HJURP_C; 1.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   SUPFAM; SSF55455; SRF-like; 1.
DR   PROSITE; PS00350; MADS_BOX_1; 1.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          1..61
FT                   /note="MADS-box"
FT                   /evidence="ECO:0000259|PROSITE:PS50066"
FT   REGION          178..221
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          373..471
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..403
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   471 AA;  51127 MW;  8D34230DE27293C2 CRC64;
     MGRKKIQITR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS TNKLFQYAST
     DMDKVLLKYT EYNEPHESRT NSDIVEALNK KENKGCESPD PDSSYALTPR TEEKYKKINE
     EFDNMIKSHK IPAVPPPNFE MPVSIPVSSH NSLVYSNPVS SLGNPNLLPL AHPSLQRNSM
     SPGVTHRPPS AGNTGGLMGG DLTSGAGTSA GNGYGNPRNS PGLLVSPGNL NKNMQAKSPP
     PMNLGMNNRK PDLRVLIPPG SKNTMPSVSE DVDLLLNQRI NNSQSAQSLA TPVVSVATPT
     LPGQGMGGYP SAISTTYGTE YSLSSADLSS LSGFNTASAL HLGSVTGWQQ QHLHNMPPSA
     LSQLGACTST HLSQSSNLSL PSTQSLNIKS EPVSPPRDRT TTPSRYPQHT RHEAGRSPVD
     SLSSCSSSYD GSDREDHRNE FHSPIGLTRP SPDERESPSV KRMRLSEGWA T
//