ID A0A2K6CRE6_MACNE Unreviewed; 199 AA.
AC A0A2K6CRE6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000026197.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000026197.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC {ECO:0000256|ARBA:ARBA00004135}. Cell projection, dendrite
CC {ECO:0000256|ARBA:ARBA00004279}. Cell projection, filopodium
CC {ECO:0000256|ARBA:ARBA00004486}. Cell projection, growth cone
CC {ECO:0000256|ARBA:ARBA00004624}.
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
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DR RefSeq; XP_011739185.1; XM_011740883.1.
DR AlphaFoldDB; A0A2K6CRE6; -.
DR SMR; A0A2K6CRE6; -.
DR Ensembl; ENSMNET00000050477.1; ENSMNEP00000026197.1; ENSMNEG00000036539.1.
DR GeneID; 105481355; -.
DR CTD; 2258; -.
DR GeneTree; ENSGT00940000163347; -.
DR OrthoDB; 5348469at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000036539; Expressed in temporal lobe and 6 other cell types or tissues.
DR GO; GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.
DR GO; GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.
DR GO; GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd00058; FGF; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF77; FIBROBLAST GROWTH FACTOR 13; 1.
DR Pfam; PF00167; FGF; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT REGION 167..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 199 AA; 22275 MW; D73D2E43AAA1414F CRC64;
MSGKVTKPKE EKDASKEPQL KGIVTKLYSR QGYHLQLQAD GTIDGTKDED STYTLFNLIP
VGLRVVAIQG VQTKLYLAMN SEGYLYTSEL FTPECKFKES VFENYYVTYS SMIYRQQQSG
RGWYLGLNKE GEIMKGNHVK KNKPAAHFLP KPLKVAMYKE PSLHDLTEFS RSGSGTPTKS
RSVSGVLNGG KSMSHNEST
//
