ID A0A2K6D486_MACNE Unreviewed; 559 AA.
AC A0A2K6D486;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Microtubule-associated protein {ECO:0000256|RuleBase:RU000686};
GN Name=MAP2 {ECO:0000313|Ensembl:ENSMNEP00000030720.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000030720.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000030720.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|RuleBase:RU000686}.
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DR RefSeq; XP_011738734.1; XM_011740432.1.
DR AlphaFoldDB; A0A2K6D486; -.
DR Ensembl; ENSMNET00000055140.1; ENSMNEP00000030720.1; ENSMNEG00000038593.1.
DR GeneID; 105481123; -.
DR CTD; 4133; -.
DR GeneTree; ENSGT00940000156597; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000038593; Expressed in temporal lobe and 11 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR InterPro; IPR027324; MAP2/MAP4/Tau.
DR InterPro; IPR001084; MAP_tubulin-bd_rpt.
DR InterPro; IPR018459; RII-bd_1.
DR PANTHER; PTHR11501; MICROTUBULE-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR11501:SF15; MICROTUBULE-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF10522; RII_binding_1; 1.
DR Pfam; PF00418; Tubulin-binding; 4.
DR PROSITE; PS00229; TAU_MAP_1; 2.
DR PROSITE; PS51491; TAU_MAP_2; 4.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|RuleBase:RU000686};
KW Cytoskeleton {ECO:0000256|RuleBase:RU000686};
KW Microtubule {ECO:0000256|RuleBase:RU000686};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 85..103
FT /note="RII binding"
FT /evidence="ECO:0000259|Pfam:PF10522"
FT REGION 1..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 559 AA; 59003 MW; 4D3A698942572EF9 CRC64;
MADERKDEAK APHWTSAQLT EASAHSHPPE IKDQGGAGEG LVRSANGFPY REDEEGAFGE
HGSQGTYSNT KENGINGELT SADRETAEEV SARIVQVVTA EAVAVLKGEQ EKEAQHKDQT
AALPLAAEET ANLPPSPPPS PASEQTVTVE EAAGGESALA PSVFKQAKDK VSNSTLSKIP
ALQGSTKSPR YSSACPSTTK RATFSDSLLM QPTSAGSTDR LPYSKSGNKD GVTKSPEKRS
SLPRPSSILP PRRGVSGDRD ENSFSLNSSI SSSARRTTRS EPIRRAGKSG TSTPTTPGST
AITPGTPPSY SSRTPGTPGT PSYPRTPHTP GTPKSAILVP SEKKVAIIRT PPKSPATPKQ
LRLINQPLPD LKNVKSKIGS TDNIKYQPKG GQVRILNKKI DFSKVQSRCG SKDNIKHSAG
GGNVQIVTKK IDLSHVTSKC GSLKNIRHRP GGGRVKIESV KLDFKEKAQA KVGSLDNAHH
VPGGGNVKID SQKLNFREHA KARVDHGAEI ITQSPGRSSV ASPRRLSNVS SSGSINLLES
PQLATLAEDV TAALAKQGL
//
