ID A0A2K6D4A7_MACNE Unreviewed; 492 AA.
AC A0A2K6D4A7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Microtubule-associated protein {ECO:0000256|RuleBase:RU000686};
GN Name=MAP2 {ECO:0000313|Ensembl:ENSMNEP00000030741.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000030741.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000030741.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|RuleBase:RU000686}.
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DR AlphaFoldDB; A0A2K6D4A7; -.
DR Ensembl; ENSMNET00000055161.1; ENSMNEP00000030741.1; ENSMNEG00000038593.1.
DR GeneTree; ENSGT00940000156597; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000038593; Expressed in temporal lobe and 11 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR InterPro; IPR027324; MAP2/MAP4/Tau.
DR InterPro; IPR001084; MAP_tubulin-bd_rpt.
DR InterPro; IPR018459; RII-bd_1.
DR PANTHER; PTHR11501; MICROTUBULE-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR11501:SF15; MICROTUBULE-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF10522; RII_binding_1; 1.
DR Pfam; PF00418; Tubulin-binding; 4.
DR PROSITE; PS00229; TAU_MAP_1; 2.
DR PROSITE; PS51491; TAU_MAP_2; 4.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|RuleBase:RU000686};
KW Cytoskeleton {ECO:0000256|RuleBase:RU000686};
KW Microtubule {ECO:0000256|RuleBase:RU000686};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 85..103
FT /note="RII binding"
FT /evidence="ECO:0000259|Pfam:PF10522"
FT REGION 1..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 492 AA; 52243 MW; 1BDE6978B29D7FBB CRC64;
MADERKDEAK APHWTSAQLT EASAHSHPPE IKDQGGAGEG LVRSANGFPY REDEEGAFGE
HGSQGTYSNT KENGINGELT SADRETAEEV SARIVQVVTA EAVAVLKGEQ EKEAQHKDQT
AALPLAAEET ANLPPSPPPS PASEQTVTVE EEPNVLFVFS NQDGVTKSPE KRSSLPRPSS
ILPPRRGVSG DRDENSFSLN SSISSSARRT TRSEPIRRAG KSGTSTPTTP GSTAITPGTP
PSYSSRTPGT PGTPSYPRTP HTPGTPKSAI LVPSEKKVAI IRTPPKSPAT PKQLRLINQP
LPDLKNVKSK IGSTDNIKYQ PKGGQVRILN KKIDFSKVQS RCGSKDNIKH SAGGGNVQIV
TKKIDLSHVT SKCGSLKNIR HRPGGGRVKI ESVKLDFKEK AQAKVGSLDN AHHVPGGGNV
KIDSQKLNFR EHAKARVDHG AEIITQSPGR SSVASPRRLS NVSSSGSINL LESPQLATLA
EDVTAALAKQ GL
//
