ID A0A2K6DB40_MACNE Unreviewed; 911 AA.
AC A0A2K6DB40;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Erythrocyte membrane protein band 4.1 like 4B {ECO:0000313|Ensembl:ENSMNEP00000033139.1};
GN Name=EPB41L4B {ECO:0000313|Ensembl:ENSMNEP00000033139.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000033139.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000033139.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K6DB40; -.
DR STRING; 9545.ENSMNEP00000033139; -.
DR Ensembl; ENSMNET00000057583.1; ENSMNEP00000033139.1; ENSMNEG00000039820.1.
DR GeneTree; ENSGT00940000158331; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000039820; Expressed in colon and 8 other cell types or tissues.
DR GO; GO:0045177; C:apical part of cell; IEA:Ensembl.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR GO; GO:0031032; P:actomyosin structure organization; IEA:Ensembl.
DR GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR GO; GO:0051549; P:positive regulation of keratinocyte migration; IEA:Ensembl.
DR GO; GO:0042060; P:wound healing; IEA:Ensembl.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13186; FERM_C_NBL4_NBL5; 1.
DR CDD; cd17204; FERM_F1_EPB41L4B; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR030698; EHM2_FERM_F1.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF18; BAND 4.1-LIKE PROTEIN 4B; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 84..384
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 911 AA; 100553 MW; 3AA5A4C18B97A22E CRC64;
ADSSAPEPFG RRRFQATATR GRGGAGAAGV GRAPTGAAGG PAAASSSALP AAPGGSVFPA
GGGPLLTGGA AVHISAAGAA KATLYCRVFL LDGTEVSVDL PKHAKGQDLF DQIVYHLDLV
ETDYFGLQFL DSAQVAHWLD HAKPIKKQMK IGPAYALHFR VKYYSSEPNN LREEFTRYLF
VLQLRHDILS GKLKCPYETA VELAALCLQA ELGECELPEH TPELVSEFRF IPNQTEAMEF
DIFQRWKECR GKSPAQAELS YLNKAKWLEM YGETVFAFCI LLCDDLLEPS TDCHFGRDGC
EYSLGLTPTG ILIFEGANKI GLFFWPKITK MDFKKSKLTL VVVEDDDQGR EQEHTFVFRL
DSARTCKHLW KCAVEHHAFF RLRTPGNSKS NRSDFIRLGS RFRFSGRTEY QATHGSRLRR
TSTFERKPSK RYPSRRHSTF KGCVFFILSK TNPEVHNYQP QYHPNIHPSQ PRWHPHSPNV
SYPLPSPVLS SSDRLPFGIE ENGGTPFLTA ASGRHHHQHQ HQHQHQHHSN YSLSLTLENK
EGPLRSPNSS SKSLTKLSPG TPALFSEAAA HLKKLELETV KAAGPWPPLH ININKAEEKK
VSEKTLQTPL LPSPVADHVK CNILKAQLEN ASRVNIQGGK EESMFVNINK KSSLQDANVR
SPIPIRVETA QPAAEKPEIK PPRVRKLTRQ YSFDEDDLPP DLAEAVGVTT ATTTNTTTAA
TQVSVPLPSP KVQNVSSPHK SEGKGQLSPG AKSPSDRGGA FTLEPGDLLM DFTEATPLAE
PASNPHCAHS RCSPPLSLPM KEETTGVCMY PPIKTRLIKT FPADTMNPFP DTFTTGPQFT
ADFRDSKLQC CPGPSSPLIP AATLRPLTET VSTVQTIYTT RKPVSLAASA ETLRQELERE
KMMKRLLMTE L
//
