ID A0A2K6DDQ9_MACNE Unreviewed; 3077 AA.
AC A0A2K6DDQ9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 10-FEB-2021, entry version 17.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMNEP00000034042};
GN Name=CENPF {ECO:0000313|Ensembl:ENSMNEP00000034042};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000034042, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000034042}
RP NUCLEOTIDE SEQUENCE.
RA Hughes D.S., Liu Y., Murali S., Raveendran M., Korchina V., Wang M.,
RA Jhangiani S., Bandaranaike D., Bellair M., Blankenburg K., Chao H.,
RA Dahdouli M., Dinh H., Doddapaneni H., English A., Gnanaolivu R., Gross S.,
RA Jayaseelan J., Jones J., Khan Z., Kovar C., Kurapati P., Le B., Lee S.,
RA Matakis S., Mathew T., Narasimhan A., Ngo D., Okwuonu G., Ongeri F.,
RA Osuji N., Otenyo P., Patel E., Qu C., Quiroz J., Raj R., Rajbhandari K.,
RA Reid J.G., Santibanez J., Skinner E., Vee V., Wang Y., Weissenberger G.,
RA Xin Y., Zou X., Han Y., Muzny D.M., Richards S., Worley K.C., Rogers J.,
RA Gibbs R.A.;
RT "Pig-tailed Macaque reference genome and diversity panel.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMNEP00000034042}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2018) to UniProtKB.
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DR Ensembl; ENSMNET00000058489; ENSMNEP00000034042; ENSMNEG00000040232.
DR GeneTree; ENSGT00730000111187; -.
DR Proteomes; UP000233120; Unplaced.
DR GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 3.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1892..2034
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2130..2269
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2312..2451
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2933..2976
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 208..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1668..1687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1719..1745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2852..2941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2987..3077
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 164..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 280..377
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 386..413
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 418..501
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 505..615
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 623..650
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 658..685
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 725..745
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 832..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 899..996
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1029..1109
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1118..1159
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1203..1244
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1286..1313
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1397..1417
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1548..1611
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1623..1645
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1789..1816
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1824..1844
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1910..1930
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1945..1965
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1969..1996
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2001..2049
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2057..2077
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2106..2133
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2141..2224
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2228..2277
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2292..2315
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2323..2459
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2474..2543
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2561..2602
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2617..2662
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2709..2736
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2744..2788
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2799..2826
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2891..2919
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2992..3043
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3045..3062
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3077 AA; 352999 MW; 1D35EEF073FE5F97 CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDSLEAALQK QKQKVENEKT
EGTNLKRENQ RLMEICESLE KTKQKISHEL QVKESQVNFQ EGQLNSGKKQ IEKLEQELKR
CKSELERSQQ AAQSADVSLN PCNTPQKIFT TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
LEAEVKALQA KKASQTLPQT TMNHRDIARH QASSSVFSWQ QEKTPSHLSS NSQKTPIRRD
FCASYFSGEQ EVTPSRSTLQ IGKRDANSSF FDNSSSPHLL EQLKVQNQEL RSKINELELR
LQGQEKEMKG QVNKFQELQL QLEKVKVELI EKEKVLNKCR DELVRTTAQY DQASTKCTAL
EQKLKKLSED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQECIQVKAR
LTQELQQAKN MHNVLQAELD KVTAVKQQLE KNLEEFKQKL CRAEQASQAS QIKEDELRRS
VEEMKKENNL LKSQSEQKAR EVCHLEAELK NVKQYLNQSQ NFAEEMKVKN TSQETMLRDL
QEKINQQENS LTLEKLKLAV AELEKQRDCS QDLLKKREHH IEQLNDKLSK TEKESKALLS
ALELKKKEYE ELKEEKTLFS CWKSENEKLL TQMESEKENL QSKINHLETC LKTQQIKSHE
YNERVRTLEM DRENLSVEIR NLHNVIDSKS VEVETQKLAY VELQQKAEFS DQKHQKEIEN
MCLKTSQLTG QVEDLEHKLQ LLSNEIMDKD RCYQDLHAEY ESLRDLLKSK DASLVTNEDH
QRSLLAFDEQ PAMHNSFANI IEEQGSMLSE RSECHLEADQ SPKNSAILQN RVDSLEFSLE
SQKQMNSDLQ KQCEELVQMK GEIEENLMKA EQMHQSFVAE TSQRISKLQE DTSAHQNVVA
ETLSALENKE KELQLLNDKL ATEQAEIQEL KQSNHLLEDS LKELQLLSET LSLEKKEMSS
IISLNKREIE ELTQENETLK EINASLNQEK MNLIQKSESF ANYIDEREKS ISELSDQYKQ
ENLILLQRCE ETGNAYEDLS QKYKAAQEKN SKLECLLNEC TSLCENRKNE LEQLKEAFAK
EHQEFLTKLA FAEERNQNLM LELETVQQDL RSEMTDTRNN SKSETDGLKQ EIMTLKEEQN
KMQKEVNDLL QENEQLMKVM KTKHECQNLE SEPIRNCVKE RESERNQCNF KPQMDLEVKE
ISLDSYNVQL VQLEAMLRNM ELKLQESEKE KECLQHELQI IRGDLETRNL QDMQSQEISG
LKDCEVDAEE RYISVLHGLS TSQNDNAHLE CSLQTAMNKL NELEKICEIL QAEKCELVTE
LNDSRSECIT ATRKMAEEVG KLVNEVKILN DDSGLLHGEL VEDIPGGELG EQANEQHPMC
LAPLDESNSY EHLTLSNKEV QMHFAELQEK FSSLQSEHKI LHDQHCQMSS KMSELQTYID
SLKAENLVLS TNLRNFQGDL VKEMQPGLEE GLVPSLSSCV PDSPSLSSLG DSSFYKALLE
QTGEMSLLNN LEGTVSANQC SVDEVFCSSL LEENLTKKEM PSAPAKGVEE LESLCEAYRQ
SLEKLEEKME SQGIMKNKEI QELQQLLSSE RQELDCLRKQ YLSENEQWQQ KLTSVTLEME
SKLAAEKKQT EQLSLELEVA RLQLQGLDLS SRSLLGIDTE DAIQGRNESC DISKEHTSET
TERTPKHDVH QICDKDVQQD LRLDIEKITE TGAVKLTGEC SGEQSQDTNC KTPGEDKSQG
SSECISELSF SGANASVPMD ILGNQENTQN LQLRVKETSN ENLRLLHVIE ERDRKVENLL
NEMKELDSKL HLQEVQLMTK IEACIELEKL VGELKKENSD LSEKLEYFSC DNQELLQRVE
SSEGLNSNLE MHADKSSHED IEDNVAKVND SWKERFLDVE NELSSIRSEK ANIEHQALSL
EADLEIVQTE KLCLEKDNEN NQKVIVCLEE ELSVVTSERN QLRGELDTMS KKTMELDQLS
EKMKEKTQEL ESHRSEYLHC IQVAEAKLKE KTELLQTLSS DVSELLKDKT HLQEKLQSLE
KDSQALSLTK CELENQIAQL NKERELLVKE SESLQARLNE SDYEKLNVSK ALEAALVEKG
EFALRLSSTQ EEVHQLRRGI EKLRVRIEAD ERKQLHVAEK LKERERENDS LKDKVENLER
ELQMSEENQE LVILDAENSK AEVETLKTQI EEMARSLKVF ELDLVTLRSE KENLTKQIQD
KQGQVSVLDK LLSSVKSLLE EKEQAEIQIK EESKTAVEML QNQLKELNEA VAALCGDQET
MKATEQSLDP SVEEAHQLRN SIEKLRARLE TDEKKQLCVL EQLKESEHHA DLLKSRVENL
ERELEIAGKN QEHAALEAEN SKGEVETLKA KIEGMTQSLR DLELDLATVR SEKENLTNKL
QKEQERISEL KIINSSFENI LREKEQEKVQ MKEKSNTAME MLQTQLKELH ERVTALHNDQ
EACKAKEQNL SSQVDCLELE KAQLLQGLDE AKNNNIVLQS SVNGLIQEVE DGKQKLEKKD
EEISRLKNQI QDQEQLVSKL SQVEGEHQFW KKQNLELGNL TVELEQKIQV LQSKNTSLQD
TLEVLQSSYK NLENELELTK MDKISFVEKV NTMTAKETEL QREMHEMAQK TAELQEELSG
EKNRLTGELQ LLLEEIKSSK VNCMAEGTGG KEGKLGLLYT NKQYEIEIHT YREKLTSKEE
CLSSQTLEMD LLKSSKEELN NSLKATTEAL EELKKTKMDN LKYVNQLKKE NERAQGKIKL
LIKSCKQLEE EKEILQKELS KLQAAQEKQK TGTVMDIKVD ELTTEIKELK EALEEKTKEA
DEYLDKYCSL LISHEKLEKA KEMLETQVAH LCSQQSKPDS RGSPLLDPVV PGPSPILSAA
EKRLSSGQKK ASGKRQRSSG IWENGRGPTP STPETFSKKS KKAVMSGIHP AEDTEGTQFE
PEGLPEVVKK GFADIPTGKT SPYILRRTTM ATRTSPRLAA QKLALSPLSL GKENLAESSK
PTAGGSRSQK VKVAQQSPVD SDTILREPTT KSLLVNNLPE RSPTDSPREG LRVKRGRLAP
HPKVGLEPKG SENCKVQ
//
