ID A0A2K6DGQ8_MACNE Unreviewed; 1458 AA.
AC A0A2K6DGQ8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=ATPase family AAA domain containing 2B {ECO:0000313|Ensembl:ENSMNEP00000035112.1};
GN Name=ATAD2B {ECO:0000313|Ensembl:ENSMNEP00000035112.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000035112.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000035112.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_011736470.1; XM_011738168.1.
DR STRING; 9545.ENSMNEP00000035112; -.
DR Ensembl; ENSMNET00000059566.1; ENSMNEP00000035112.1; ENSMNEG00000040701.1.
DR GeneID; 105479837; -.
DR CTD; 54454; -.
DR GeneTree; ENSGT00550000074694; -.
DR OrthoDB; 2783776at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000040701; Expressed in thymus and 12 other cell types or tissues.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0070577; F:lysine-acetylated histone binding; IEA:Ensembl.
DR CDD; cd05528; Bromo_AAA; 1.
DR CDD; cd19517; RecA-like_Yta7-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR045199; ATAD2-like.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23069; AAA DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23069:SF5; ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2B; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00674; AAA; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 975..1038
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 244..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1217..1257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1310..1331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..110
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..278
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1458 AA; 165030 MW; AD0BBA1D30972F73 CRC64;
MVNTRKSSLR LLGSKSPGPG PGPGAGAEPG ATGGSSHFIS SRTRSSKTRA ASCPAAKAGG
SGGAGVTLDE ARKAEVDGSL SDSHVSPPAK RTLKQPDSVC KDKSKSRSTG QREEWNLSTG
QARLTSQPGA TLPNGHSSLS LRSHPLRGEK KGDGDLSCIN GDMEVRKSCR SRKNRFESVN
QSLLFDQLVN STAEAVLQEM DNINIRRNRR SGEVERLRMW TDTEFENMDM YSRVKRRRKS
LRRNSYGIQN HHEVSTEGEE EESQEEDGDI EVEEAEGEEN DRPYNLRQRK TVDRYQAPPI
VPAHQKKREN TLFDIHRSPA RRSHIRRKKH AIHSSDTTSS DEERFERRKS KSMARARNRC
LPMNFRAEDL ASGILRERVK VGASLADVDP MNIDKSVRFD SIGGLSHHIH ALKEMVVFPL
LYPEIFEKFK IQPPRGCLFY GPPGTGKTLV ARALANECSQ GDKKVAFFMR KGADCLSKWV
GESERQLRLL FDQAYLMRPS IIFFDEIDGL APVRSSRQDQ IHSSIVSTLL ALMDGLDNRG
EIVVIGATNR LDSIDPALRR PGRFDREFLF NLPDQKARKH ILQIHTRDWN PKLSDAFLGE
LAEKCVGYCG ADIKALCTEA ALIALRRRYP QIYASSHKLQ LDVSSIVLSA QDFYHAMQNI
VPASQRAVMS SGHALSPIIR PLLERSFNNI LAVLQKVFPH AEISQSDKKE DIETLILEDS
EDENALSIFE THCHSGSPKK QSSAAAIHKP YLHFTMSPYH QPTSYRPRLL LSGERGSGQT
SHLAPALLHT LERFSVHRLD LPALYSVSAK TPEESCAQIF REARRTVPSI VYMPHIGDWW
EAVSETVRAT FLTLLQDIPS FSPIFLLSTS ETMYSELPEE VKCIFRIQYE EVLYIQRPIE
EDRRKFFQEL ILNQASMAPP RRKHAALCAM EVLPLALPSP PRQLSESEKN RMEDQEENTL
RELRLFLRDV TKRLATDKRF NIFSKPVDIE EVSDYLEVIK EPMDLSTVIT KIDKHNYLTA
KDFLKDIDLI CSNALEYNPD KDPGDKIIRH RACTLKDTAH AIIAAELDPE FNKLCEEIKE
ARIKRGLSVT SEQINPHSTG ARKTETRVEE AFRHKQRNPM DVWHNSANKC AFRVRRKSRR
RSQWGKGIIK KRKVNNLKKD EEDTKFADYE NHAEDRKLLE NGEFEVSTDC HEENGEETGD
LSMTNDESSC DIMDMDQGQR LNNGAGTKEN FASTEEESSN ESLLVNSSSS LNPEQTSRKE
TFLKGNCLNG EASTDSFEGI PVLECQNGKL EVVSFCDSGD KCSSEQKILL EDQSKEKPET
SIENHGDDPE KLEALECSNN EKLEPDPDVE VKDAELDKEG ASKVKKYRKL ILEQAKTTSL
ELVPEEPSEP VPPLIVDRER LKKLLDLLVD KSNNLAVDQL ERLYSLLSQC IYRHRKDYDK
SQLVEEMERT VHMFETFL
//
