ID   A0A2K6DHX0_MACNE        Unreviewed;       433 AA.
AC   A0A2K6DHX0;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Paired box 1 {ECO:0000313|Ensembl:ENSMNEP00000035496.1};
GN   Name=PAX1 {ECO:0000313|Ensembl:ENSMNEP00000035496.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000035496.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000035496.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A2K6DHX0; -.
DR   Ensembl; ENSMNET00000059954.1; ENSMNEP00000035496.1; ENSMNEG00000040896.1.
DR   GeneTree; ENSGT00940000159137; -.
DR   OMA; MEHTYGE; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000040896; Expressed in thymus and 1 other cell type or tissue.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00131; PAX; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR043182; PAIRED_DNA-bd_dom.
DR   InterPro; IPR001523; Paired_dom.
DR   InterPro; IPR043565; PAX_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR45636:SF15; PAIRED BOX PROTEIN PAX-1; 1.
DR   PANTHER; PTHR45636; PAIRED BOX PROTEIN PAX-6-RELATED-RELATED; 1.
DR   Pfam; PF00292; PAX; 1.
DR   PRINTS; PR00027; PAIREDBOX.
DR   SMART; SM00351; PAX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS00034; PAIRED_1; 1.
DR   PROSITE; PS51057; PAIRED_2; 1.
PE   4: Predicted;
KW   Paired box {ECO:0000256|ARBA:ARBA00022724};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          74..200
FT                   /note="Paired"
FT                   /evidence="ECO:0000259|PROSITE:PS51057"
FT   REGION          398..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   433 AA;  45394 MW;  1D19450D222C175E CRC64;
     MRDAPLRGSS VPLPTPSRTQ AVCPWTPSCL GTHRSPLEVR LGAVPRSAWG PWANPPGVFF
     PACSLLSGAS AEQTYGEVNQ LGGVFVNGRP LPNAIRLRIV ELAQLGIRPC DISRQLRVSH
     GCVSKILARY NETGSILPGA IGGSKPRVTT PNVVKHIRDY KQGDPGIFAW EIRDRLLADG
     VCDKYNVPSV SSISRILRNK IGSLAQPGPY EASKQPPSQP TLPYNHIYQY PYPSPVSPTG
     AKMGSHPGVP GTAGHVSIPR SWPSAHSVSN ILGIRTFMEQ TGALAGSEGT TYSPKMEDWA
     GVNRTAFPTT PAVNGLEKPA LEADIKYTQS ASTLSAVGGF LPACAYPASN QHGVYSAPGG
     GYLAPGPPWP PAQGPPLAPP GAGVAVHGGE LAAAMTFKHP NREVADRKPP SPGSKAPDAL
     SSLHGLPIPA STS
//