ID A0A2K6DJG8_MACNE Unreviewed; 1780 AA.
AC A0A2K6DJG8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Shroom family member 3 {ECO:0000313|Ensembl:ENSMNEP00000036075.1};
GN Name=SHROOM3 {ECO:0000313|Ensembl:ENSMNEP00000036075.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000036075.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000036075.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the shroom family.
CC {ECO:0000256|ARBA:ARBA00006469}.
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DR Ensembl; ENSMNET00000060536.1; ENSMNEP00000036075.1; ENSMNEG00000041162.1.
DR GeneTree; ENSGT00940000157778; -.
DR OMA; TDPLGMQ; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000041162; Expressed in colon and 8 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR Gene3D; 6.10.250.3120; -; 1.
DR InterPro; IPR014800; ASD1_dom.
DR InterPro; IPR014799; ASD2_dom.
DR InterPro; IPR027685; Shroom_fam.
DR PANTHER; PTHR15012; APICAL PROTEIN/SHROOM-RELATED; 1.
DR PANTHER; PTHR15012:SF33; PROTEIN SHROOM3; 1.
DR Pfam; PF08688; ASD1; 1.
DR Pfam; PF08687; ASD2; 1.
DR PROSITE; PS51306; ASD1; 1.
DR PROSITE; PS51307; ASD2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00637};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 706..808
FT /note="ASD1"
FT /evidence="ECO:0000259|PROSITE:PS51306"
FT DOMAIN 1453..1741
FT /note="ASD2"
FT /evidence="ECO:0000259|PROSITE:PS51307"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 869..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1086..1356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1421..1447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..603
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 785..809
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 909..925
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..968
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1146..1160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1237..1271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1279..1297
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1306..1321
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1421..1440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1780 AA; 193735 MW; D7B38738D4381939 CRC64;
MESLEPSGAY PPCHLSPAKS TGSIDQLSHF HNKRDSAYSS FSTSSSILEY PPPSISARER
SSSMDNTSAR GGLLEGMRQA DIRYVKTVYD TRRGVSAEYE VNSSALLLQG REARASADGQ
GYDKWSNIPR GKGVPPPSWS QQCPSSLETA TDNLPPKVGA PLPPARSDSY AAFRHRERPS
SWSSLDQKRL CRPQANSLGS LKSPFIEEQL HTVLEKSPEN SPPVKPKHNY TQKAQPGQPL
LPTSIYPVPS LEPHFAQVPQ PSVSSNGLVY PALAKESGYI APQGACNKMA TIDENGNQNG
SSRPGFAFCQ PLEHDLLSPV EKKPEATVKY VPSKVHFSSV PENEEDASLK RHLTPPQGNS
PHSNERKSTH SNKPSSHPHS LKCPQAQAWP AGEDKRSSRL SEPWEGDFQE DHNANLWRRL
DREGLGQSLS GNFGKTKSAF SSLQNIPESL RRHSSLELGR GAQEGYPGGR PTCAVNTKAE
DPGRKAAPDL GSHLDRQLSY PRPEGRTGAS TSFHSTDPRP EELPAASHPH TSSLGRRGPG
PGSASALQGF QYGKPHCSVL EKVSKFEQRE QGSQRPSVGG SGFGQNYRPH RTVSTSSTSG
NDFEEIKAHI RFSESAEPLG NGEQHFKNGE LTLEEASRQP CGQQLSGGAS DSGRGPQRPD
ARLLRSQSTF QLSSEPEREP EWRDRPGSPE SPLLDAPFSR AYRNSIKDAQ SRVLGATSFR
RRDLELGAPV ASKSWRSRPS SAHVGLRSPE APASASPHTP RERHSVTPAE GDLARPVPAA
ARRGARRRLT PEQKKRSYSE PEKMNEVGVA EEAEPTPLGP QRNGMRFPES NVADRRRLFE
RDGKACSTLS LSGPELKQFQ QSALADYIQR KTGKRPTSAA GCSLQEPGPL RERAQSAYLQ
PGPAALEPSG LTSASSLSSL REPSLQPRRE ATLLPATVAE TPQAPRDRSS SFAGGRRLWE
RRRGDPQVPR ELLSGANGGT RGTQRVDETH REPSSWGARA GKSMSAEDLL ERSDVLAGPV
HVRSRSSPAT ADKHQDVLLG QDNGFGLVKD PCYLAGPGSR SLSCSERGQE EMPLLFHHPT
PRWGGSGCKA IGDSSVPSEC PGTPDHQRQA SRTPCPRPPL AGTQGQLTDT RAAPLTPLGT
PLPSAVPSGY CSQDGQTGRQ PLPPYTPAMT HRSNGHTLTQ PPGPRGCEGD GPEHGVEEGT
RKRVSLPQWP PPSRVKWAHA GREDSLPEES SAPEFANLKH YQKQQSLPSS CSTSDPDTPL
GTPSTPGRIS LRISESVLRD SPPPREDYED EVFVRDLHPK ATSSPTFETL PPPPPPPPSQ
ETLVYSMDDF PPPPPHAVCE AQLDSEDPEG LRPSSNKLSK VTIARERHMP GAAHVVGSQT
LASRLQTSIK GSEAESTPPS FMSVHPQFAG SLGGQPAPIR TQSLTHDPVN GTQGLEKKVN
SDPQKSSEDI RTEALAKEIV HQDKSLADIL DPDSRLKTTM DLMEGLFPRD VNLLKENSVK
RKAIQRTVSS SGCEGKRNED KEAVSMLVNC PAYYSVSAPK AELLNKIKEM PAEVNEEEEQ
ADVNEKKAEL IGSLTHKLET LQEAKGSLLM DIKLNNALGE EVEALISELC KPNEFDKYRM
FIGDLDKVVN LLLSLSGRLA RVENVLSGLG EDASNEERSS LYEKRKILAG QHEDARELKE
NLDRRERIVL GILANYLSEE QLQDYQHFVK MKSTLLIEQR KLDDKIKLGQ EQVKCLLESL
PSDFIPKAGA LALPPNLTSE PTPAGGCTFS GVFPTLTSPL
//
