ID A0A2K6DQE9_MACNE Unreviewed; 598 AA.
AC A0A2K6DQE9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=EBF family member 4 {ECO:0000313|Ensembl:ENSMNEP00000038154.1};
GN Name=EBF4 {ECO:0000313|Ensembl:ENSMNEP00000038154.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000038154.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000038154.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004489}.
CC -!- SIMILARITY: Belongs to the COE family. {ECO:0000256|ARBA:ARBA00010340,
CC ECO:0000256|RuleBase:RU004489}.
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DR RefSeq; XP_011739640.1; XM_011741338.1.
DR AlphaFoldDB; A0A2K6DQE9; -.
DR SMR; A0A2K6DQE9; -.
DR Ensembl; ENSMNET00000062628.1; ENSMNEP00000038154.1; ENSMNEG00000042057.1.
DR GeneID; 105481618; -.
DR CTD; 57593; -.
DR GeneTree; ENSGT00950000182859; -.
DR OMA; GGVCWPG; -.
DR OrthoDB; 3641706at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000042057; Expressed in temporal lobe and 2 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd11606; COE_DBD; 1.
DR CDD; cd01175; IPT_COE; 1.
DR Gene3D; 1.10.287.4280; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.3180; Transcription factor COE1, DNA-binding domain; 1.
DR InterPro; IPR032200; COE_DBD.
DR InterPro; IPR038173; COE_DBD_sf.
DR InterPro; IPR032201; COE_HLH.
DR InterPro; IPR038006; COE_IPT.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR003523; Transcription_factor_COE.
DR InterPro; IPR018350; Transcription_factor_COE_CS.
DR PANTHER; PTHR10747; TRANSCRIPTION FACTOR COE FAMILY MEMBER; 1.
DR PANTHER; PTHR10747:SF36; TRANSCRIPTION FACTOR COE4; 1.
DR Pfam; PF16422; COE1_DBD; 1.
DR Pfam; PF16423; COE1_HLH; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS01345; COE; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|RuleBase:RU004489};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004489};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004489};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004489};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004489};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004489};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004489};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004489}.
FT DOMAIN 251..335
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT REGION 444..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 63998 MW; 95FE8C8FB46C02CC CRC64;
MEALPRGGLN LKEEPLLPAG LGSVRSWMQG AGILDASTAA QSGVGLARAH FEKQPPSNLR
KSNFFHFVLA MYDRQGQPVE VERTAFIDFV EKDREPGAEK TNNGIHYRLR LVYNNGLRTE
QDLYVRLIDS MSKQAIIYEG QDKNPEMCRV LLTHEIMCSR CCDRKSCGNR NETPSDPVII
DRFFLKFFLK CNQNCLKNAG NPRDMRRFQV VVSTTVSVDG HVLAVSDNMF VHNNSKHGRR
ARRLDPSEAA TPCIKAISPG EGWTTGGATV IVIGDNFFDG LQVVFGNVLV WSELITPHAI
RVQTPPRHIP GVVEVTLSYK SKQFCKGAPG RFVYTALNEP TIDYGFQRLQ KVIPRHPGDP
ERLPKEVLLK RAADLAEALY GVPGSNQELL LKRAADVAEA LYSTPRAPGP LGPLAPSHPH
PAVVGINAFS SPLAIAVGDA TPGPEPGYAR SCSSASPRGF APSPGSQQSG YGSGLGAGLG
GYGAPGVAGL GVPGSPSFLN GSTATSPFAI MPSSPPLAAA SSMSLPAAAP TTSVFSFSPV
NMISAVKQRS AFAPVLRPPS SPPQACPRAH GEGLPDQSFE DSDKFHSPAR GLQGLAYS
//
