UniProt: A0A2K6DRE6

Database: UniProt
Entry: A0A2K6DRE6_MACNE

LinkDB:  A0A2K6DRE6_MACNE 
Original site:  A0A2K6DRE6_MACNE

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Ontology (2)   
   GO (2)   
Gene (3)   
   ENSEMBL-UP (3)   
Protein domain (6)   
   InterPro (3)   
   Pfam (1)   
   PROSITE (1)   
   SMART (1)   
All databases (11)   

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ID   A0A2K6DRE6_MACNE        Unreviewed;        75 AA.
AC   A0A2K6DRE6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=ADP-ribosylation factor GTPase-activating protein 2 {ECO:0000256|ARBA:ARBA00039244};
DE   AltName: Full=Zinc finger protein 289 {ECO:0000256|ARBA:ARBA00043100};
GN   Name=ARFGAP2 {ECO:0000313|Ensembl:ENSMNEP00000038493.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000038493.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000038493.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Golgi
CC       apparatus membrane {ECO:0000256|ARBA:ARBA00004255}; Peripheral membrane
CC       protein {ECO:0000256|ARBA:ARBA00004255}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004255}.
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DR   AlphaFoldDB; A0A2K6DRE6; -.
DR   Ensembl; ENSMNET00000062974.1; ENSMNEP00000038493.1; ENSMNEG00000042175.1.
DR   GeneTree; ENSGT00940000155568; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000042175; Expressed in skeletal muscle tissue and 12 other cell types or tissues.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR001164; ArfGAP_dom.
DR   InterPro; IPR038508; ArfGAP_dom_sf.
DR   PANTHER; PTHR45686; ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED; 1.
DR   PANTHER; PTHR45686:SF10; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 2; 1.
DR   Pfam; PF01412; ArfGap; 1.
DR   PRINTS; PR00405; REVINTRACTNG.
DR   SMART; SM00105; ArfGap; 1.
DR   SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR   PROSITE; PS50115; ARFGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00288}; Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW   Transport {ECO:0000256|ARBA:ARBA00022448};
KW   Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00288};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00288}.
FT   DOMAIN          11..75
FT                   /note="Arf-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50115"
SQ   SEQUENCE   75 AA;  8294 MW;  27895F2DE9B27DF3 CRC64;
     MAAEPNKTEI QTLFKRLRAV PTNKACFDCG AKNPSWASIT YGVFLCIDCS GVHRSLGVHL
     SFISWVPRKA SGPRR
//

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