ID A0A2K6DRH8_MACNE Unreviewed; 632 AA.
AC A0A2K6DRH8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=ZFP90 zinc finger protein {ECO:0000313|Ensembl:ENSMNEP00000038523.1};
GN Name=ZFP90 {ECO:0000313|Ensembl:ENSMNEP00000038523.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000038523.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000038523.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR AlphaFoldDB; A0A2K6DRH8; -.
DR Ensembl; ENSMNET00000063004.1; ENSMNEP00000038523.1; ENSMNEG00000042243.1.
DR GeneTree; ENSGT00940000162132; -.
DR OMA; TLEDTWD; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000042243; Expressed in temporal lobe and 12 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 13.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF137; ZINC FINGER PROTEIN 8; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 12.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 13.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 8.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 13.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 10..81
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 207..234
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 250..277
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 278..305
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 306..333
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 334..361
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 362..389
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 390..417
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 446..473
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 493..520
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 521..548
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 549..576
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 577..604
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 605..632
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 632 AA; 72577 MW; 525F3DAEFD6F39B5 CRC64;
ISPRPAWESV TFKDVSVDFT QEEWYHVDPA QRSLYRDVML ENYSHLVSLG YQVSKPEVIF
KLEQGEEPWI SEGEIQRPFC PDWKTRLEVK SSHLQQDVSE VSHCTHDLSH ATLEDSWDVS
SQLNRQQENW KRHLGSEAST QKKIVTPQGS FEQSKFGENS RLNTNLVTQL NIPARIRPSE
CETPGSNLEH NADLLNQNNI LAKKKPYKCD KCRKAFIHRS SLTKHEKTHK GDGAFPNGTD
QGIYPGKKHH ECTDCGKTFL WKTQLTEHQR IHTGEKPFEC NVCGKAFRHS SSLGQHENAH
TGEKPYQCSL CGKAFQRSSS LVQHQRIHTG EKPYRCNLCG RSFRHGTSLT QHEVTHSGEK
PFQCKECGKA FSRCSSLVQH ERTHTGEKPF ECSICGRAFG QSPSLYKHMR IHKRGKPYQS
NNYSIDFKHN SSLTQDESTL TEVKSYHCND CGEDFSHITD FTDHQRIHTG ENPYDCEQAF
SQQAISHPGE KPYQCNVCGK AFKRSTSFIE HHRIHTGEKP YECNECGEAF SRRSSLTQHE
RTHTGEKPYE CIDCGKAFSQ SSSLIQHERT HTGEKPYECN ECGRAFRKKT NLHDHQRIHT
GEKPYSCKEC GKNFSRSSAL TKHQRIHTRN KL
//
