ID   A0A2K6DSB6_MACNE        Unreviewed;      1268 AA.
AC   A0A2K6DSB6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Astrotactin 1 {ECO:0000313|Ensembl:ENSMNEP00000038800.1};
GN   Name=ASTN1 {ECO:0000313|Ensembl:ENSMNEP00000038800.1};
OS   Macaca nemestrina (Pig-tailed macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000038800.1, ECO:0000313|Proteomes:UP000233120};
RN   [1] {ECO:0000313|Ensembl:ENSMNEP00000038800.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_011744435.1; XM_011746133.1.
DR   AlphaFoldDB; A0A2K6DSB6; -.
DR   Ensembl; ENSMNET00000063283.1; ENSMNEP00000038800.1; ENSMNEG00000042291.1.
DR   GeneID; 105484476; -.
DR   CTD; 460; -.
DR   GeneTree; ENSGT00390000003140; -.
DR   OrthoDB; 4157619at2759; -.
DR   Proteomes; UP000233120; Unplaced.
DR   Bgee; ENSMNEG00000042291; Expressed in temporal lobe and 3 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001764; P:neuron migration; IEA:InterPro.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   InterPro; IPR040685; Annexin-like.
DR   InterPro; IPR045574; ASTN1_2_Fn3.
DR   InterPro; IPR045575; ASTN_1_2_N.
DR   InterPro; IPR026995; Astrotactin.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR020864; MACPF.
DR   PANTHER; PTHR16592; -; 1.
DR   PANTHER; PTHR16592:SF8; ASTROTACTIN-1; 1.
DR   Pfam; PF18411; Annexin_2; 1.
DR   Pfam; PF19743; ASTN1_2_fn3; 1.
DR   Pfam; PF19441; ASTN_1_2_N; 1.
DR   SMART; SM00181; EGF; 3.
DR   SMART; SM00457; MACPF; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..1268
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014361560"
FT   TRANSMEM        151..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          462..499
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|SMART:SM00181"
FT   DOMAIN          603..644
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|SMART:SM00181"
FT   DOMAIN          651..700
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|SMART:SM00181"
FT   DOMAIN          803..991
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|SMART:SM00457"
FT   REGION          340..380
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        351..365
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1268 AA;  140975 MW;  03ADE02BD50BFBAF CRC64;
     MALAGLCALL ACCWGPAAVL ATAAGDVDPS KELECKLKSI TVSALPFLRE NDLSIMHSPS
     ASEPKLLFSV RNDFPGEMVV VDDLENTELP YFVLEISGNT EDIPLVRWRQ QWLENGTLLF
     HIHHQDGAPS LPGQDPTEEP QHESAEEELR ILHISVMGGM IALLLSILCL VMILYTRRRW
     CKRRRVPQPQ KSASAEAANE IHYIPSVLIG GHGRESLRNA RVQGHNSSGT LSIRETPILD
     GYEYDITDLR HHLQRECMNG GEDFASQVTR TLDSLQGCNE KSGMDLTPGS DNAKLSLMNK
     YKDNIIATSP VDSNHQQATL LSHTSSSQRK RINNKARAGS AFLNPEGDSG TEAENDPQLT
     FYTDPSRSRR RSRVGSPRSP VNKTTLTLIS ITSCVIGLVC SSHVNCPLVV KITLHVPEHL
     IADGSRFILL EGSQLDASDW LNPAQVVLFS QQNSSGPWAM DLCARRLLDP CEHQCDPETG
     ECLCYEGYMK DPVHKHLCIR NEWGTNQGPW PYTIFQRGFD LVLGEQPSDK IFRFTYTLGE
     GMWLPLSKSF VIPPAELAIN PSAKCKTDMT VMEDAVEVRE ELMTSSSFDS LEVLLDSFGP
     VRDCSKDNGG CSKNFRCISD RKLDSTGCVC PSGLSPMKDS SGCYDRHIGV DCSDGFNGGC
     EQLCLQQMAP FPDDPTLYNI LMFCGCIEDY KLGVDGRSCQ LITETCPEGS DCGESRELPM
     NQTLFGEMFF GYNNHSKEVA AGQVLKGTFR QNNFARGLDQ QLPDGLVVAT VPLENQCLEE
     ISEPTPDPDF LTGMVNFSEV SGYPVLQHWK VRSVMYHIKL NQVAISQALS NALHSLDGAT
     SRADFVALLD QFGNHYIQEA IYGFEESCSI WYPNKQVQRR LWLEYEDISK GNSPSDESEE
     RERDPKVLTF PEYIASLSDS GTKRMAAGVR MECQSKGRCP SSCPLCHVTS SPDTPAEPVL
     LEVTKAAPIY ELVTNNQTQR LLQEATMSSL WCSGTGDVIE DWCRCDSTAF GADGLPTCAP
     LPQPVLRLST VHEPSSTLVV LEWEHSEPPI GVQIVDYLLR QEKVTDRMDH SKVETETVLS
     FVDDIISGAK SPCAMPSQVP DKQLTTISLI IRCLEPDTIY MFTLWGVDNT GRRSRPSDVI
     VKTPCPVVDD VKAQEIADKI YNLFNGYTSG KEQQTAYNTL LDLGSPTLHR VLYHYNQHYE
     SFGEFTWRCE DELGPSQQGR MKVPPKSHPI HLTSDQTGER ISLIWPAVTC SYKLPQKTII
     EDILFSYF
//