ID A0A2K6DT05_MACNE Unreviewed; 572 AA.
AC A0A2K6DT05;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=MAGUK p55 subfamily member 7 {ECO:0000256|ARBA:ARBA00017019};
GN Name=MPP7 {ECO:0000313|Ensembl:ENSMNEP00000039051.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000039051.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000039051.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC {ECO:0000256|ARBA:ARBA00004536}. Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}.
CC -!- SIMILARITY: Belongs to the MAGUK family.
CC {ECO:0000256|ARBA:ARBA00007014}.
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DR AlphaFoldDB; A0A2K6DT05; -.
DR Ensembl; ENSMNET00000063534.1; ENSMNEP00000039051.1; ENSMNEG00000042436.1.
DR GeneTree; ENSGT00940000156232; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000042436; Expressed in thymus and 12 other cell types or tissues.
DR GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR CDD; cd00071; GMPK; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd12033; SH3_MPP7; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR014775; L27_C.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR035599; MPP7_SH3.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23122:SF39; MAGUK P55 SUBFAMILY MEMBER 7; 1.
DR PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF02828; L27; 2.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00569; L27; 2.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS51022; L27; 2.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 6..60
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 61..118
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 135..216
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 224..294
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 364..556
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
SQ SEQUENCE 572 AA; 65284 MW; E2169D491792C600 CRC64;
LPTLTTDLGL YELLAALPAQ LQPHVDSQED LTFLWDMFGE KSLHSLVKIH EKLHYYEKQS
PVPILHGAAA LADDLAEELQ NKPLNSEIRE LLKLLSKPSV KALLSVHDTV AQKNYDPVLP
PMPEDIDDEE DSVKIIRLVK NREPLGATIK KDEHTGAITV ARIMRGGAAD RSGLIHVGDE
LREVNGIPVE DKRPEEIIQI LAQSQGAITF KIIPGIKEET PSKEGKMFIK ALFDYNPNED
KAIPCKEAGL SFKKGDILQI MSQDDATWWQ AKHEGDANPR AGLIPSKHFQ ERRLALRRPE
ILVQPLKVSN RKSSGFRRSF RLSRKDKKTN KSMYECKKSD QYDTADVPTY EEVTPYRRQT
NEKYRLVVLV GPVGVGLNEL KRKLLISDTQ HYGVTVPHTT RARRSQESDG VEYIFISKHL
FETDVQNNKF IEYGEYKNNY YGTSIDSVRS VLAKNKVCLL DVQPHTVKHL RTLEFKPYVI
FIKPPSIERL RETRKNAKII SSRDDQGAAK PFTEEDFQEM IKSAQIMESQ YGHLFDKIII
NDDLTVAFNE LKTTFDKLET ETHWVPVSWL HS
//
