ID A0A2K6DTI7_MACNE Unreviewed; 770 AA.
AC A0A2K6DTI7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Ssemaphorin 4F {ECO:0000313|Ensembl:ENSMNEP00000039233.1};
GN Name=SEMA4F {ECO:0000313|Ensembl:ENSMNEP00000039233.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000039233.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000039233.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR RefSeq; XP_011711996.1; XM_011713694.1.
DR AlphaFoldDB; A0A2K6DTI7; -.
DR STRING; 9545.ENSMNEP00000039233; -.
DR Ensembl; ENSMNET00000063718.1; ENSMNEP00000039233.1; ENSMNEG00000042562.1.
DR GeneID; 105465302; -.
DR KEGG; mni:105465302; -.
DR CTD; 10505; -.
DR GeneTree; ENSGT00940000159592; -.
DR OMA; PRKIVWD; -.
DR OrthoDB; 5342713at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000042562; Expressed in temporal lobe and 6 other cell types or tissues.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd11261; Sema_4F; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR047085; Sem4F_Sema_dom.
DR InterPro; IPR045791; Sema4F_C.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF72; SEMAPHORIN-4F; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF19428; Sema4F_C; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..770
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014460056"
FT TRANSMEM 659..680
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..510
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 696..725
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 83604 MW; F278075691DA5B80 CRC64;
MPASDARPRP GPGPPTASPF PLLLLAVLSG PVSGRVPRSV PRTSLPISEA DSYLTRFTVP
QTYNYSVLLV DPASHTLYVG ARDTIFALSL PFSGERPRRI DWMVPEAHRQ NCRKKGKKED
ECHNFVQILA IANASHLLTC GTFAFDPKCG VIDVSSFQQV ERLESGRGKC PFEPAQRSAA
VMAGGVLYAA TVKNYLGTEP IITRAVGRAE DWIRTDTLPS WLNAPAFVAA VALSPAEWGD
EDGDDEIYFF FTETSRAFDS YERIKVPRVA RVCAGDLGGR KTLQQRWTTF LKADLLCPGP
EHGRASSVLQ DVAVLRPELG AGTPIFYGIF SSQWEGAAIS AVCAFRPQDI RTVMNGPFRE
LKHDCNRGLP VMDNDVPQPR PGECITNNMK LRHFGSSLSL PDRVLTFIRD HPLMDRPVFP
ADGHPLLVTT DTAYLRVVAH RVTSLSGKEY DVLYLGTEDG HLHRAVRIGA QLSVLEDLAL
FPEPQPVENM KLYHSWLLVG SRTEVTQVNT TNCGRLQSCS ECILAQDPVC AWSFRLDECV
AHAGQHRGLV QDIESADVSS LCPKEPGERP VVFEVPVATA AHVVLPCSPS SAWASCVWHQ
PSGVTVLTPR RDGLEVVVTP GAMGAYACEC QEGGAARVVA AYSLVWGSQR DALSRAHTVG
AGLAGFFLGV LAASLTLLLI GRRQQRRRQR ELLARDKVGL DLGAPPSGTT SYSQDPPSPS
PEDERLPLAL AKRGSGFGGF SPPFLLDPCP SPAHIRLTGA PLATCDETSI
//
