ID A0A2K6DVJ0_MACNE Unreviewed; 391 AA.
AC A0A2K6DVJ0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Thioredoxin-interacting protein {ECO:0000256|ARBA:ARBA00039479};
GN Name=TXNIP {ECO:0000313|Ensembl:ENSMNEP00000039922.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000039922.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000039922.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the arrestin family.
CC {ECO:0000256|ARBA:ARBA00005298}.
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DR RefSeq; XP_011735151.1; XM_011736849.1.
DR AlphaFoldDB; A0A2K6DVJ0; -.
DR SMR; A0A2K6DVJ0; -.
DR STRING; 9545.ENSMNEP00000039922; -.
DR Ensembl; ENSMNET00000064413.1; ENSMNEP00000039922.1; ENSMNEG00000042880.1.
DR GeneID; 105479046; -.
DR KEGG; mni:105479046; -.
DR CTD; 10628; -.
DR GeneTree; ENSGT00940000158522; -.
DR OMA; GPQQCKQ; -.
DR OrthoDB; 22053at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000042880; Expressed in lung and 12 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0071228; P:cellular response to tumor cell; IEA:Ensembl.
DR GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR GO; GO:0051782; P:negative regulation of cell division; IEA:Ensembl.
DR Gene3D; 2.60.40.640; -; 2.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR11188; ARRESTIN DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11188:SF14; THIOREDOXIN-INTERACTING PROTEIN; 1.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; E set domains; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 174..301
FT /note="Arrestin C-terminal-like"
FT /evidence="ECO:0000259|SMART:SM01017"
SQ SEQUENCE 391 AA; 43643 MW; EBD892C7B7D74411 CRC64;
MVMFKKIKSF EVVFNDPEKV YGSGEKVAGR VIVEVCEVTR VKAVRILACG VAKVLWMQGS
QQCKQTSEYL RYEDTLLPED QPTGENEMVI MRPGNKYEYK FGFELPQGPL GTSFKGKYGC
VDYWVKAFLD RPSQPTQETK KNFEVVDLVD VNTPDLMAPV SAKKEKKVSC MFIPDGRVSV
SARIDRKGFC EGDEISIHAD FENTCSRIVV PKAAIVARHT YLANGQTKVL TQKLSSVRGN
HIISGTCASW RGKSLRVQKI RPSILGCNIL RVEYSLLIYV SVPGSKKVIL DLPLVIGSRS
GLSSRTSSMA SRTSSEMSWV DLNIPDTPEA PPCYMDIIPE DHRLESPTTP LLDDMDGAQD
SPIFMYAPEF KFMPPPTYTE VDPCILNNNV Q
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