ID A0A2K6DWI7_MACNE Unreviewed; 403 AA.
AC A0A2K6DWI7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Crumbs cell polarity complex component 1 {ECO:0000313|Ensembl:ENSMNEP00000040252.1};
GN Name=CRB1 {ECO:0000313|Ensembl:ENSMNEP00000040252.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000040252.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000040252.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; A0A2K6DWI7; -.
DR Ensembl; ENSMNET00000064744.1; ENSMNEP00000040252.1; ENSMNEG00000043019.1.
DR GeneTree; ENSGT00940000155152; -.
DR OMA; YNCLCVE; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000043019; Expressed in cerebellum and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 6.
DR Gene3D; 2.10.25.10; Laminin; 8.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR12916; CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2; 1.
DR PANTHER; PTHR12916:SF4; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1-RELATED; 1.
DR Pfam; PF00008; EGF; 7.
DR Pfam; PF12661; hEGF; 1.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00181; EGF; 8.
DR SMART; SM00179; EGF_CA; 8.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 5.
DR PROSITE; PS00022; EGF_1; 6.
DR PROSITE; PS01186; EGF_2; 5.
DR PROSITE; PS50026; EGF_3; 8.
DR PROSITE; PS01187; EGF_CA; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 57..95
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 97..133
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 135..171
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 173..209
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 211..247
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 249..286
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 288..324
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 326..382
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 66..83
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 85..94
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 123..132
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 161..170
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 199..208
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 237..246
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 314..323
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 403 AA; 43704 MW; 56C1322810C791A7 CRC64;
TQNYFSTSYK NSFCNKNNTR CLSNSCQNNS TCKGFSKDND CSCSGTANNV DKDCDNVKDP
CFSNPCQGSA TCVNTPGERS FLCKCPPGYS GTICETTIGS CGKNSCQHGG ICHQDPIYPV
CICPAGYAGR FCEIDHDECA SSPCQNGAVC QDGIDGYSCF CVPGYQGRHC DLEVDECASD
PCKNEATCLN EIGRYTCICP RDYSGINCEL EIDECWSQPC LNGATCQDAL GAYFCDCAPG
FLGDHCELNI DECASQPCLH GGLCVDGENR YSCNCTGSGF TGTHCETLMP LCWSKPCHNN
ATCEDSVDNY TCHCWPGYTG AQCEIDINEC NSNPCQSDGE CVELSSEKQY GHITGLPSTF
SYHEASGYVC ICQPGFTGEA KEMGYDLTFW HFMAEHGFNQ LGY
//
