ID A0A2K6DY62_MACNE Unreviewed; 3907 AA.
AC A0A2K6DY62;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=A-kinase anchoring protein 9 {ECO:0000313|Ensembl:ENSMNEP00000040855.1};
GN Name=AKAP9 {ECO:0000313|Ensembl:ENSMNEP00000040855.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000040855.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000040855.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
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DR Ensembl; ENSMNET00000065349.1; ENSMNEP00000040855.1; ENSMNEG00000043025.1.
DR GeneTree; ENSGT00730000110871; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000043025; Expressed in pituitary gland and 12 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0060090; F:molecular adaptor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR InterPro; IPR028745; AKAP9/Pericentrin.
DR InterPro; IPR005539; ELK_dom.
DR InterPro; IPR019528; PACT_domain.
DR PANTHER; PTHR44981:SF1; A-KINASE ANCHOR PROTEIN 9; 1.
DR PANTHER; PTHR44981; PERICENTRIN-LIKE PROTEIN, ISOFORM F; 1.
DR Pfam; PF10495; PACT_coil_coil; 1.
DR SMART; SM01188; ELK; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 437..458
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 629..650
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 659..680
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 966..986
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1688..1723
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3377..3405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 162..471
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 500..640
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 719..795
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 820..886
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 950..1005
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1149..1176
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1332..1366
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1580..1650
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1893..1993
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2023..2166
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2191..2450
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2636..2663
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2698..2767
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3126..3181
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3210..3283
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3585..3626
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3652..3679
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1702..1722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3907 AA; 453135 MW; 040AE77593245E2B CRC64;
MEDEERQKKL EAGKAKVGEP ELAQFRQRKA QSDGQNPSKK QKKKRKTTSS KHDVSAHHNL
NVDQSQCDEM YINSSQRVES TVTPESTIMR TLPGGEITSH EQVFSVELES EISTTADDYS
SEVNGCSFVM KTGKPTNLLR EEEFGVDDSY SEQGAQYSLT HLEMMESELA GKQHEIEELN
RELEEMRVTY GTEGLQQLQE FEAAIKQRDG IITQLTANLQ QARREKDETM REFLELTEQS
QKLQIQFQQL QASETLRNST HSSTAADLLQ AKQQIRTHQQ QLEEQDHLLE DYQKKKEDFT
MQISFLQEKI KVYEMEQDKK VENSNKEEIQ EKETIIEELN TKIIEEEKKT LELKDKLTAA
DKLLGELQEQ VVQKNQEIKN MKLELTNSKQ KERQSSEEIK QLMGTVEELQ KRNHKDSQFE
TDIVQRMEQE TQRKLEQLRA ELDEMYGQQI VQMKQELIRQ HVSQMEELKT RHKGEMENAL
RSYPNITVNE DQIKLMNVAI NELNIKLQDT NSQKEKLKEE LGVILEEKCA LQRQLEDLFE
ELSFSREQIQ RARQTIAEQE SKLNEAQKSL STVEDLKAEI VSASESRKEL ELKHEAEVTN
YKIKLEMLEK EKNAVLDRMA ESQEAELERL RTQLLFSHEE ELSKLKEDLE IEHQINIEKL
KDNLGIHYKQ QIDGLQNEMS QKIETMQFEK DNLITKQNQL ILEISKLKDL QQSLVNSKSE
EMTLQINELQ KEIEILRQEE KEKGTLEQEV QELQLKTELL EKQMKEKEND LQEKFTQLEA
ENSILKDEKK ALEDMLKIHT PDNQEERLIF IDSVKSKSKD SVWEKEIEIL TEENEDLKQQ
CIQLNEEIEK QRNTFSFAEK NFEVNYQELQ EEYACLLKVK DDLEDSKNKQ ELEYKSKLKA
LNEELHLQRI NPTTVKTKSS VFDEDKTFVA ETLEMGEVVE KDTTELMEKL EVTKREKLEL
SQRLADLSEQ LKQKHGEISF LNEEVKSLKQ EKEQVLLRCR ELEIIINHNR AENVQSCDTQ
VSSLSDGVVT MTSRDAEGSV SKVNKSFGEE SKIMVEDKVS FENMTTGKES KQEQLILDHL
PSVTKESSLR AAQPSENDKL QKELNVLKSE QNDLRLQMEA QRICLSLVYS THVDQVREYM
ENEKDKALCS LKEELISAQE EKIKELQKIH QLELQNTKTQ ETGDEGKPLH LLIGKLRKAV
SEECSYFLQT LCSVLGEYYT PALKCEVNAE DRENSGDYTS ENEDSELQDY RYEVQDFQEN
MHTLLNKVTE EYNKLLVLQT RLSKIWGQQT DGMKFEFGEE NLPKEETKFL SIHSQMTSLE
DSDVNHKSKL SSLQHLEKTE QLEEQVQELE SLISSLQQQL KETEQSYEAE IHYLRKRLQA
VSESTVPPSF PVDSVVITES DAQRTMYPGS CVKKNIDGTI EFSGEFGVKE ETNIVKLLEK
QYQEQLEEEV AKVIVSMSIA FAQQTELSRI SGGKENTTSS KQAHAVCHQE KQHYFNEMKL
SQDQTGFQTF ETVDVKFKEE FKPLSKELGE HGKEILLSNN DPDDIRESKD CVLTISEEMF
SKDKTFIVRQ SIHDEISVSS MDASRQLMLN EEQLEDMRQE LVRQYQEHQQ ATELLRQAHM
RQMERQREDQ EQLQEEIKRL NKQLAQRSSI DNENLVSERE RVLLEELEAL KQLSLAGREK
LCCELRNSST QTQNGNENQG EAEEQTFKEK ELDRKPEHVP PEILSNERYA LQKANNRLLK
ILLEVVKTTA AVEETIGRHV LGILDRSSKS QSSASLIWRS EAEASVKSCV HEEHTRVTDE
SIPSYSGSDM PRNDINMWSK VTEEGTELSQ RLVRSGFAGT EIDPENEELV LNISSRLQAA
VEKLLEAISE TSSQLEHAKV TQTELMRESF RQKQEATESL KCQEDLRERL HEESRAREQL
AVELSKAEGV IDGYADEKTL FERQIQEKTD IIDRLEQELL CASNRLQELE AEQQQIQEER
ELLSRQKEAM KAEAGPVEQQ LLQETEKLMK EKLEVQCQAE KVRDDLQKQV KALEIDVEEQ
VSRFIELEQE KNAELMDLRQ QNQALEKQLE KMRKFLDEQA IDREHERDVF QQEIQKLEQQ
LKVVPRFQPI SEHQTREVEQ LTNHLKEKTD KCSELLLSKE QLQRDIQERN EEIEKLEFRV
RELEQALLVS ADTFQKVEDR KQFGAVEAKP ELSLEVQLQA ERDAIDRKEK EITNLEEQLE
QFREELENKN EEVQQLHMQL EIQKKESTTR LQELEQENKL FKDDMEKLGL AIKESDAVST
QDQHVLFGKF AQIIQEKEVE IDQLNEQIMK LQQQLKITTD NKVIEEKNEL IRDLETQIEC
LMSDQECVKR NREEEIEQLN EVIEKLQQEL ANIGQKTLVD AHSLPEEADS LKHQLDMVIA
EKLALEQQVE TTNEEMTFTK NILKETNFKM NQLTQELFSL KRERESMEKI QSIPGKSVNM
AIDDLSKDKP ELEVVLTEDA LKSLENQTYL KSFEENGKGS IINLETRLLQ LESTVSAKDL
ELTQCYKQIK DMQEQGQSEI EVLQKKILNL QKILEEKVAA ALVSQIQLEA VQEYAKFCQD
NQTISSEPER TNIQNLNQLR EDESGSNISA LTLRISELES QLVEMHTSLI LGKEQVEIAE
KNVLEKEKKL LELQKLLEGN EKKQGGKERK RSPQDFEVLK TTTELFHSNE ESGFLNELEA
LRAESVATKA ELTGYKEKTE KLQGELLIKE TNMASLQKDL SQVRDHLAEA KEKLSILEKE
DKTAVQENKK ACMFEPLPVK LSKSIASQTD GTLKVNSSNQ TPQILVKNAG IQIDLQSECS
SEEVTEIISQ FTEKIEKMQE LHAAEILDME SRHISETETL KREHYVAVQL LKEECGTLKA
VIQRLRSKEV FGFYNIQMIF FILDSRSDWG QGIYLTHSQG FDTASEGQGE ESESATDSFP
KKIKGLLRAV HNEGMQVLSL TESPYNDGED HSIQQISESW LEERKAYLST ISSLKDLITK
MQLQREAEVY DSSQSHESFS DWRGELLLAL QQVFLEERSV LLAAFRTELT ALGTTDAVGL
LNCLEQRIQE QGVEYQAAME YLQKADRRSL LSEIQALHAQ MNGRKITLKR EQENEKSSQE
LLEYNIQQKQ SQMLEMQVEL SSMKDRATEL QEQLSSEKMV VAELRSELAQ TKLELETTLK
AQHKHLKELE AFRLEVKDKT DEVHLLNDTL ASEQKKSREL QWALEKEKAK LGHSEERDKE
ELEDLKFSLE SQKQRNLQLN LLLEQQKQLL DESQQKIESQ RMLYDAQLSE EHGRNLELQV
LLESEKVRIR EMSSTLDRER ELHAQLQSND GTGQSRPSLP SEDLLKELQK QLEEKHSRIV
ELLNETEKYK LDSLQTRQQM EKDRQVHRKT LQTEQEANTE GQKKMHELQS KVEDLQRQLE
EKRQQVYKLD LEGQRLQGIM QEFQKQELER EEKRESRRIL YQNLNEPATW SLTSDRTRNW
VLQQKIEGET KESNYAKLIE MNGGGTGCNH ELEMSRQKLQ CVASKLQVLA QKASKRLQFE
IADDEDFIWV QENIDEIILQ LQKLIGQQGE EPSLVSPSTS CGSLTERLLR QNAELTGHIS
QLTEEKNDLR NMVMKLEEQI RWYRQTGAGR DNSSRFSLNG GANIEAIIAS EKEVWNREKL
TLQKSLKRAE AEVYKLKAEL RNDSLLQTLS PDSEHVTLKR IYGKYLRAES FRKALIYQKK
YLLLLLGGFQ ECEDATLALL ARMGGQPAFT DLEVITNRPK GFTRFRSAVR VSIAISRMKF
LVRRWHRVTG SGSININRDG FGLNQGAEKT DSFFHSSGGL ELYGEPRHTT YRSRSDLDYI
RSPLPFQNRY PGTPADFIPG SLACSQLQNY DPDRALTDYI TRLEALQRRL GTIQSGSTTQ
FHAGMRR
//
