ID A0A2K6DYS9_MACNE Unreviewed; 375 AA.
AC A0A2K6DYS9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Serpin B5 {ECO:0000256|ARBA:ARBA00024076};
GN Name=SERPINB5 {ECO:0000313|Ensembl:ENSMNEP00000041079.1};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000041079.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000041079.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space
CC {ECO:0000256|ARBA:ARBA00004239}.
CC -!- SIMILARITY: Belongs to the serpin family. Ov-serpin subfamily.
CC {ECO:0000256|ARBA:ARBA00006426}.
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DR RefSeq; XP_011731603.1; XM_011733301.1.
DR AlphaFoldDB; A0A2K6DYS9; -.
DR STRING; 9545.ENSMNEP00000041079; -.
DR Ensembl; ENSMNET00000065575.1; ENSMNEP00000041079.1; ENSMNEG00000043388.1.
DR GeneID; 105476997; -.
DR KEGG; mni:105476997; -.
DR CTD; 5268; -.
DR GeneTree; ENSGT00940000160674; -.
DR OMA; IFAPLCT; -.
DR OrthoDB; 3218836at2759; -.
DR Proteomes; UP000233120; Unplaced.
DR Bgee; ENSMNEG00000043388; Expressed in thymus.
DR GO; GO:0001533; C:cornified envelope; IEA:Ensembl.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0016528; C:sarcoplasm; IEA:Ensembl.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
DR GO; GO:0060512; P:prostate gland morphogenesis; IEA:Ensembl.
DR GO; GO:0050678; P:regulation of epithelial cell proliferation; IEA:Ensembl.
DR CDD; cd02057; serpinB5_maspin; 1.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR000240; Serpin_B9/Maspin.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR InterPro; IPR033836; SERPINB5_serpin_dom.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR PANTHER; PTHR11461:SF55; SERPIN B5; 1.
DR Pfam; PF00079; Serpin; 1.
DR PRINTS; PR00676; MASPIN.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233120}.
FT DOMAIN 13..375
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 375 AA; 42219 MW; 0D6388291C6BA8BD CRC64;
MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF
ENVKDVPFGF QTVTSDVNKL SSFYSLKLIK RLYIDKSLNL STEFISSTKR PYAKELETVD
FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET
KECPFRVNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDMEDES
TGLEKIEKQL NSESLLQWTN PSTMANAKVK LSIPKFKVEK MIDPKASLEN LGLKHIFSED
TSDFSGMSET KGVALSNVIH KVRLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH
NKTRNIIFFG KFCSP
//
