ID A0A2K6E041_MACNE Unreviewed; 447 AA.
AC A0A2K6E041;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
OS Macaca nemestrina (Pig-tailed macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9545 {ECO:0000313|Ensembl:ENSMNEP00000041533.1, ECO:0000313|Proteomes:UP000233120};
RN [1] {ECO:0000313|Ensembl:ENSMNEP00000041533.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC {ECO:0000256|ARBA:ARBA00003767}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR AlphaFoldDB; A0A2K6E041; -.
DR STRING; 9545.ENSMNEP00000041533; -.
DR Ensembl; ENSMNET00000066032.1; ENSMNEP00000041533.1; ENSMNEG00000043575.1.
DR GeneTree; ENSGT00940000154437; -.
DR OMA; YSHAYTQ; -.
DR Proteomes; UP000233120; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 2.
DR InterPro; IPR045914; Zn532-like.
DR InterPro; IPR041697; Znf-C2H2_11.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR47222:SF3; ZINC FINGER PROTEIN 532; 1.
DR PANTHER; PTHR47222; ZINC FINGER PROTEIN 532-RELATED; 1.
DR Pfam; PF16622; zf-C2H2_11; 1.
DR SMART; SM00355; ZnF_C2H2; 7.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000233120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 192..220
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 222..250
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 159..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 51338 MW; AB729061F53F7C1C CRC64;
LGDRGKPYCK TTTIKTLIKN CLHYTRRVGF RCVHCNVVYS DVAALKCPIC PMAFKSAPST
YSHAYTQHPG IKIGEPKIIQ KCFMCDTVFT LQTLLYRHFD QHIENQKVSV FKCPDRSLLY
AEKQLMMDHI KSMHGTLKSI EGPPNLSINL PLSIKSVTQN SADQNKEDTK SLNGKEKLEK
KSPFPKVASP GWTCWECNHL FMQRDVYISH MRKEHGKQMK KHPCCQCDKS FSSSHSLCWH
NRIKHKGIRK VRTFTKQLML EKHVQLMHGI KDPDLKEMTD TTNEEETEIK EDTKVPSPKQ
KLEEPVLEFR PPRGAITQPL KELKINVFKV HKCAMCGFTT KNLLQFHEHI PQHKSDGSSY
QRRECGLCYT SHVSLSRHLF IVHKLKELRP VSKQNGAGED NQQENKPSHK DESPDGAMSD
RKCKVCAKTF ETEAAFIKSK RMSSAEK
//
